Results 51 to 60 of about 406 (135)

Consistent use injectable and oral chondroprotectors in patients with osteoarthritis and lower back pain. Case report [PDF]

Consilium Medicum
Osteoarthritis (OA) is a disease of the entire joint, including structural changes in hyaline articular cartilage, subchondral bone, ligaments, capsule, synovial membrane and periarticular muscles.
Olga A. Shavlovskaya, Igor D. Romanov, Irina A. Bokova   +2 more
doaj   +1 more source

Native Collagen II Relieves Bone Impairment through Improving Inflammation and Oxidative Stress in Ageing db/db Mice

Molecules, 2021
Ageing-related bone impairment due to exposure to hyperglycemic environment is scarcely researched. The aim was to confirm the improvement effects of undenatured type II collagen (UC II) on bone impairment in ageing db/db mice, and the ageing model was ...
Rui Fan, Yuntao Hao, Xinran Liu, Jiawei Kang, Jiani Hu, Ruixue Mao, Rui Liu, Na Zhu, Meihong Xu, Yong Li   +9 more
doaj   +1 more source

New pharmaconutraceutical Chondroguard®TRIO for the prevention of musculoskeletal diseases and nutritional support for patients with osteoarthritis and nonspecific back pain: an assessment of clinical options. Resolution of the Multidisciplinary Expert Council

Неврология, нейропсихиатрия, психосоматика, 2023
In recent decades, there has been an increase in the prevalence and medical and social burden of osteoarthritis (OA) and nonspecific back pain in all countries of the world. The First Multidisciplinary Bilateral Russia-Uzbekistan Expert Council presented
Al. B. Danilov, A. M. Lila, Yo. N. Majidova, O. A. Gromova, O. N. Tkacheva, I. V. Sarvilina, A. Yu. Kochish, A. G. Nazarenko, N. V. Zagorodniy, T. B. Minasov, L. I. Alekseeva, E. A. Taskina, Yu. V. Kotovskaya, E. N. Dudinskaya, A. V. Rozanov, E. Yu. Solovieva, O. A. Shavlovskaya, M. N. Sharov, P. R. Kamchatnov, A. P. Rachin, E. R. Barantsevich, D. A. Iskra, E. Z. Yakupov, F. I. Devlikamova, A. E. Barulin, M. V. Nesterova, T. G. Sakovets, A. N. Barinov, I. N. Dolgova, N. V. Zabolotskikh, E. V. Zonova, L. A. Shchepankevich, V. A. Parfenov, A. T. Dzhurabekova, S. Z. Khakimova   +34 more
doaj   +1 more source

Piroxicam‐Collagen‐Based Sponges for Medical Applications

International Journal of Polymer Science, Volume 2019, Issue 1, 2019., 2019
Depending on the concentration of the drug and/or the method of administration, drugs could be used in various ways. To take full advantage of the drug beneficial properties in oral medical interventions but also in other types of surgery, like plastic surgery, general surgery, or gynecological surgery, the drug concentration as well as the ...
Daniel-Cristian Ioan, Ileana Rău, Grațiela Teodora Tihan, Roxana Gabriela Zgârian, Mihaela Violeta Ghica, Mădălina Georgiana Albu Kaya, Elena Cristina Dinu-Pîrvu, Patrizia Paolicelli   +7 more
wiley   +1 more source

Pharmacotherapy of pain in musculoskeletal diseases: evolution and revolution of views

Неврология, нейропсихиатрия, психосоматика, 2022
The article presents new views on the treatment of pain syndromes in musculoskeletal diseases, in particular in osteoarthritis (OA) of various localizations (gonarthrosis, coxarthrosis).
O. A. Shavlovskaya, I. V. Sarvilina, O. A. Gromova, M. N. Sharov, I. A. Bokova, Y. S. Prokofieva, N. I. Shavlovskiy   +6 more
doaj   +1 more source

Cilia protein IFT88 regulates extracellular protease activity by optimizing LRP‐1–mediated endocytosis

The FASEB Journal, Volume 32, Issue 12, Page 6771-6782, December 2018., 2018
ABSTRACT Matrix protease activity is fundamental to developmental tissue patterning and remains influential in adult homeostasis. In cartilage, the principal matrix proteoglycan is aggrecan, the protease‐mediated catabolism of which defines arthritis; however, the pathophysiologic mechanisms that drive aberrant aggrecanolytic activity remain unclear ...
Clarissa R. Coveney, Isabella Collins, Megan Mc Fie, Anastasios Chanalaris, Kazuhiro Yamamoto, Angus K. T. Wann   +5 more
wiley   +1 more source

Disease-modifying osteoarthritis drugs (DMOADs): new trends in osteoarthritis therapy

Фармакоэкономика, 2023
The review examines pharmacological agents that can have potential disease-modifying osteoarthritis drugs (DMOADs) status. DMOADs prevent the progression and further structural joint damage (structure-modifying effect), leading to a decrease in symptoms ...
O. A. Shavlovskaya, О. А. Gromova, A. Yu. Kochish, Yu. D. Yukhnovskaya, I. D. Romanov, I. A. Bokova   +5 more
doaj   +1 more source

Efficacy and safety of undenatured collagen type II in modulating knee joint function in healthy and osteoarthritis subjects: a systematic review and meta-analysis

Critical Public Health
Collagen has emerged as a potential pharmacotherapeutic intervention for knee osteoarthritis (OA). This study evaluates the effectiveness and safety of undenatured collagen type II among patients with knee OA and healthy subjects without joint-related ...
Cuiqing Chang, Yimin Zhao, Wei Liu
doaj   +1 more source

Innovations in Edible Packaging Films, Coatings, and Antimicrobial Agents for Applications in Food Industry

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 4, July 2025.
ABSTRACT Packaging reduction, particularly in terms of single‐use plastic (SUP) packaging waste, as well as restrictions on specific packaging formats and regulatory requirements, are driving the demand for sustainable packaging solutions. Notably, within the category of SUP products, packaging accounts for the highest share at 40%. Therefore, advanced
Lokesh Kumar, Preeti Tyagi, Lucian Lucia, Lokendra Pal   +3 more
wiley   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source