Results 111 to 120 of about 2,756,571 (326)

Why has under-5 mortality decreased at such different rates in different countries?

open access: yesJournal of Health Economics, 2016
Controlling for socioeconomic and geographic factors, under-5 mortality (5q0) in developing countries has been declining at about 2.7% per year, a high rate of 'technical progress'. This paper adduces theoretical and empirical reasons for rejecting the usual specification of homogeneous technical progress across countries and uses a panel of 95 ...
Jamison, Dean T.   +2 more
openaire   +3 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

A Novel CPAP Device With an Integrated Oxygen Concentrator for Low Resource Countries: In Vitro Validation and Usability Test in Field

open access: yesIEEE Open Journal of Engineering in Medicine and Biology
Goal: To develop and validatea novel neonatal non-invasive respiratory support device prototype designed to operate in low-resource settings. Methods: The device integrates a blower-based ventilator and a portable oxygen concentrator.
Sofia Poletto   +9 more
doaj   +1 more source

Excess under-5 female mortality across India: a spatial analysis using 2011 census data [PDF]

open access: yes, 2018
Background Excess female mortality causes half of the missing women (estimated deficit of women in countries with suspiciously low proportion of females in their population) today.
Bora, J.K.   +3 more
core   +1 more source

Double burden of under-5 mortality in LMICs

open access: yesThe Lancet Global Health, 2022
Macharia, Peter M, Beňová, Lenka
openaire   +2 more sources

Trends in under-5 mortality rates and the HIV/AIDS epidemic.

open access: yesBulletin of the World Health Organization, 2000
The prevalence of human immunodeficiency virus (HIV) among adults and mortality rates among under-5-year-olds have increased or stagnated in many countries. The objective of this study was to investigate whether there is a link between under-5 mortality trends and the prevalence of HIV among adults and, if so, to assess the magnitude of the effect of ...
openaire   +4 more sources

Commentary: Monitoring trends in under-5 mortality: better believe it's true [PDF]

open access: yesInternational Journal of Epidemiology, 2004
Together with the proportion of people whose income is less than one US dollar a day the under-5 mortality rate is one of the most closely watched indicators of human development. In September 2000 in the United Nations Millennium Declaration 189 nations committed themselves to reducing this indicator of human suffering by two-thirds over the period ...
openaire   +3 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study [PDF]

open access: yes, 2003
OBJECTIVES: To identify clinical indicators of immediate, early, and late mortality in children at admission to a sub-Saharan district hospital and to develop prognostic scores. DESIGN: Prospective cohort study.
Berkley, JA   +8 more
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

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