Results 71 to 80 of about 35,714 (290)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

SUSTAINABLE DEVELOPMENT DIRECTIONS OF RURAL TOURISM OF TIMOK REGION

open access: yesEkonomika Poljoprivrede (1979), 2020
In Eastern Serbia in the Timok Region, the cult of household hospitality is still fostered. The Timok region belongs to the underdeveloped parts of Serbia and starting from the fact that the growth of local economy capacity also leads to overall ...
Biljana Ilić   +2 more
doaj   +1 more source

Obstacles to the globalisation of corporate research and development in technologically underdeveloped countries [PDF]

open access: yes, 2013
Over two decades, the globalisation of research and development (R&D) has become a subject of considerable academic interests. The majority of studies concerning it describe this phenomenon in developed countries.
Omar, AM
core  

How life satisfaction interacts with travel satisfaction and perceived accessibility in an underdeveloped urban region

open access: yesUrban, Planning and Transport Research
While the relationship between daily travel and life satisfaction has been widely studied, its implications for transportation planning and policy remain significant.
Hamza Yasin   +2 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A study on the adequacy about the establishment of the planning region in the spatial development policy of underdeveloped regions : In case of Sang-ju City [PDF]

open access: yes, 2004
본 논문은 우리나라의 여러 낙후지역개발 관련 법률과 제도들의 공간단위 설정의 적합성과 문제점을 비판적으로 고찰한 논문이다. 지역개발에 있어 그 대상이 되는 지역은 개발의 목표 달성을 위해 그에 상응하는 적합한 공간단위로 설정될 필요가 있다. 현행의 여러 낙후지역개발사업들은 개발지역의 공간단위 설정이 각 지역개발사업별로 다양한 범위와 편차를 보이고 있고, 그 적합성과 효율성에 대한 논의들은 부족한 것이 현실이다.
이정섭
core  

Tourism-based development opportunities for rural areas. Example of an underdeveloped region (Siklós district) [PDF]

open access: yes, 2023
The study aims to answer the question of how effectively cities of an underdeveloped rural area (Siklós district in Hungary) can involve the surrounding settlements in the tourism economy, thereby promoting the development of rural areas.
Hoványi, Gábor   +2 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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