Results 121 to 130 of about 142,290 (306)

Influencing factors associated with the underweight BMI subgroup.

open access: yes, 2018
Influencing factors associated with the underweight BMI subgroup.
Hua Fu (178428)   +2 more
core   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

Comparison of the WHO Child Growth Standards with the NCHS for Estimation of Malnutrition in Birjand-Iran

open access: yesInternational Journal of Preventive Medicine, 2014
Background: Anthropometric indices are widely used to assess the health and nutritional status of children The aim of the present study was determination of malnutrition and compare estimates of under nutrition among young children under 2 years of age ...
Kokab Namakin   +4 more
doaj  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

What Should I Do if My Child Is Underweight?

open access: yes, 2013
Tips on how you know if your child is underweight and what you should do if your child is ...
Serrano, Elena L.   +1 more
core  

In vitro fertilization in underweight women: focus on obstetric outcome [PDF]

open access: yes
In vitro fertilization in underweight women: focus on obstetric ...
Bellver Pradas, José
core   +1 more source

Impact of the agricultural projects co-financed by the partners of help to the development on the poverty of households of the Territory of Isangi, in RD Congo: Factor Predictive and construction of trajectory

open access: yesRevue Marocaine des Sciences Agronomiques et Vétérinaires, 2019
The projects agricultural co financed by the partners to the development of the RDC permitted to improve the income of households of Territory of Isangi of 22.9%, but this improvement has impacted very weakly the socioeconomic and human conditions of ...
Bienvenu MOKILI LILALA   +2 more
doaj  

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