Characteristics and Management of Patients With Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain: A Retrospective Multicenter Study [PDF]
Purpose Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical symptoms and psychosocial effects that significantly impair patients’ quality of life.
Marta Sánchez-Jareño, Luis Cea-Calvo
exaly +5 more sources
Effectiveness of proton pump inhibitor in unexplained chronic cough. [PDF]
Current guidelines recommend that patients with unexplained chronic cough undergo empirical proton pump inhibitor (PPI) treatment, but scientific evidence for this treatment is lacking.
Hye Jung Park +6 more
doaj +9 more sources
Treatment of Unexplained Chronic Cough: CHEST Guideline and Expert Panel Report [PDF]
Unexplained chronic cough (UCC) causes significant impairments in quality of life. Effective assessment and treatment approaches are needed for UCC.This systematic review of randomized controlled trials (RCTs) asked: What is the efficacy of treatment compared with usual care for cough severity, cough frequency, and cough-related quality of life in ...
Stuart Mazzone +2 more
exaly +8 more sources
Efficacy and Safety of Gefapixant, a P2X3 Receptor Antagonist, in Refractory Chronic Cough and Unexplained Chronic Cough (COUGH-1 and COUGH-2): Results From Two Double-Blind, Randomised, Parallel-Group, Placebo-Controlled, Phase 3 Trials [PDF]
BACKGROUND Gefapixant is an oral P2X3 receptor antagonist that has previously shown efficacy and safety in refractory chronic cough and unexplained chronic cough.
Jaclyn A. Smith +2 more
exaly +6 more sources
Current opinion in refractory and/or unexplained chronic cough. [PDF]
Purpose of review Otolaryngologists are vital to successfully managing chronic cough in adults. This review presents updates regarding rapidly evolving concepts in chronic cough.
Misono S, Novaleski CK.
europepmc +4 more sources
Emotions in patients with refractory or unexplained chronic cough: a multicenter, non-interventional study [PDF]
Background: Chronic cough (CC) has a negative effect on patients’ quality of life and everyday activities. Emotional reactions are an important aspect of how patients deal with illness, and CC can lead to feelings of uncertainty, loss of control ...
Ebymar Arismendi +6 more
doaj +3 more sources
New Insights Into Refractory Chronic Cough and Unexplained Chronic Cough: A 6-Year Ambispective Cohort Study. [PDF]
Purpose Only limited studies have depicted the unique features and management of refractory chronic cough (RCC) and unexplained chronic cough (UCC). These led to the initiation of this study, which reported the demographic characteristics, manifestations,
Zhang M +9 more
europepmc +5 more sources
BACKGROUND Refractory chronic cough (RCC) and unexplained chronic cough (UCC) adversely affect patients' quality of life (QoL). This multicenter, non-interventional study evaluates the relationship between cough severity and QoL and other patient ...
Francisco Javier González Barcala +2 more
exaly +3 more sources
Diagnosed and undiagnosed cough-related stress urinary incontinence in women with refractory or unexplained chronic cough: Its impact on general health status and quality of life. [PDF]
Background: Stress urinary incontinence (SUI) is common in women with chronic cough but may be overlooked. Objective: To determine the frequency of underdiagnosis of cough-related SUI and its impact on women’s general health status and quality of life ...
Arismendi E +9 more
europepmc +4 more sources
Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey. [PDF]
BackgroundChronic cough (persisting for ≥8 weeks) is a common disorder affecting approximately 5 to 10% of adults worldwide that is sometimes refractory to treatment (refractory chronic cough [RCC]) or has no identifiable cause (unexplained chronic cough
Sana Khan +6 more
doaj +3 more sources

