Results 211 to 220 of about 67,514 (293)

Gaucher disease, state of the art and perspectives

Journal of Internal Medicine, EarlyView.
Abstract Knowledge about Gaucher disease (GD), considered a model for rare diseases, has considerably increased since its discovery. The pathophysiology of this lysosomal disorder is better known, and specific therapies that can control many aspects of the disease have been developed, particularly for the most common form, Type 1 GD.
Fabrice Camou, Marc G. Berger
wiley   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso, Alejandro Schcolnik‐Cabrera, Mengyi Zhu, Erin Strachan, Xavier Clemente‐Casares, Sue Tsai   +5 more
wiley   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel, Francis Poirier‐Gravel, Marie‐Ève Paré, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Dominique Michaud, Marc‐André D'Aoust   +9 more
wiley   +1 more source

ATF4 Mediates Mitochondrial Unfolded Protein Response (UPR^mt) in Alveolar Epithelial Cells [PDF]

, 2020
H. Cui, Dechun Jiang, Nan Xie, Sami Banerjee, Ruijie Liu, Huaping Dai, Victor J. Thannickal, Gang Liu   +7 more
openalex   +1 more source

Mammalian target of rapamycin complex 1 (mTORC1); tuberous sclerosis complex tumor suppressors 1 and 2 (TSC1 and TSC2); unfolded protein response (UPR) [PDF]

, 2008

openalex   +1 more source

An Ethylene‐Response Factor LlERF092 Coordinates With LlETO1 to Improve Thermotolerance by Activating LlMBF1c in Lily

Plant Biotechnology Journal, EarlyView.
ABSTRACT Multiprotein bridging factor 1c (MBF1c) has been shown to play a critical role in plant responses to heat stress. Previous studies have implicated MBF1c roles in ethylene‐mediated thermotolerance; however, the upstream regulatory mechanisms linking MBF1c to this process remain unclear. In this study, an ethylene‐response factor (ERF), LlERF092,
Jun Xiang, Xue Gong, Qianqian Fang, Liping Ding, Yinyi Zhang, Sujuan Xu, Ting Li, Man He, Ze Wu, Nianjun Teng   +9 more
wiley   +1 more source

Red Alga Porphyridium Supports High‐Yield Production of a Functional Chimeric Hepatitis B Surface Antigen With Strong Cellular and Humoral Immunogenicity

Plant Biotechnology Journal, EarlyView.
ABSTRACT Microalgae represent promising production factories for the light‐driven, cost‐effective production of recombinant proteins. The red microalga Porphyridium purpureum displays particularly favourable transgene expression properties due to the episomal maintenance of transformation vectors at high copy numbers in the nucleus.
Ana‐Maria Pantazica, Alexander Hammel, Iuliana Caras, Irina Ionescu, Catalin Tucureanu, Adrian Onu, Maria Murace, Jihong Liu Clarke, Crina Stavaru, Norica Branza‐Nichita, Ralph Bock   +10 more
wiley   +1 more source

323 Unfolded Protein Response (UPR) and Calcium-Dependent Endoplasmic Reticulum Stress (CD-ERs) Modulate Development of Alcohol-Induced Pancreatitis

, 2013
Keisaku Sato, Tracie C. Lo, Angela Dolganiuc   +2 more
openalex   +1 more source

The secreted antigen, HP0175, ofHelicobacter pylorilinks the unfolded protein response (UPR) to autophagy in gastric epithelial cells [PDF]

, 2014
Priyanka Halder, Chandreyee Datta, Ranjeet Kumar, Arun Kumar Sharma, Joyoti Basu, Manikuntala Kundu   +5 more
openalex   +1 more source