Results 221 to 230 of about 52,959 (267)

Demethylzeylasteral alleviates myeloid leukemia through PERK/eIF2α/ATF4/CHOP-mediated cell apoptosis. [PDF]

Transl Cancer Res
Li X, He X, Zhang L, Li Z, Liu Y.
europepmc   +1 more source

Quantitative proteomic analysis identifies the unfolded protein response as a host pathway co-opted by ASFV to promote replication. [PDF]

mBio
Zhang D, Liu B, Liu H, Mao R, Cao W, Zhang X, Yang F, Wang Y, Shen C, Zhang S, Zhu Z, Zheng H.   +11 more
europepmc   +1 more source

Leukocyte mRNA sequencing reveals unfolded protein response activation in severe heat stroke in Japan. [PDF]

Front Cell Dev Biol
Nomura Y, Oda S, Matsumoto H, Togami Y, Shimazaki J, Okuzaki D, Ogura H, Oda J.   +7 more
europepmc   +1 more source

Avaliação da ativação de mecanismos apoptóticos mediados pela via UPR (unfolded protein response) em células Jurkat estimulados com a proteína Tat do HIV-1

, 2017
Jéssica Campestrini
openalex   +1 more source

Activación del sensor IRE1α de la Respuesta a proteínas mal plegadas (“Unfolded protein response”, UPR) en células dendríticas intratumorales

, 2019
Sandra Verónica Gaete-González
openalex   +1 more source

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XBP-1 and the unfolded protein response (UPR)

Nature Immunology, 2020
Laurie Glimcher and colleagues recount their work that showed how the transcription factor XBP1 and the UPR signaling pathway are interconnected during plasma cell differentiation.
Laurie H. Glimcher, Ann-Hwee Lee, Neal N. Iwakoshi   +2 more
openaire   +2 more sources

Unfolded protein response (UPR) mediated under heat stress in plants

Plant Physiology Reports, 2020
Drastic fluctuation in temperature during crop growth challenges its yield to a greater extent, thus diminishing the agricultural productivity globally. At the cellular level, protein homeostasis is altered or disturbed directly or indirectly by the high temperature.
M. K. Malini, V. S. Lekshmy, Madan Pal, Viswanathan Chinnusamy, M. Nagaraj Kumar   +4 more
openaire   +1 more source

Role of the unfolded protein response (UPR) in cataract formation

Experimental Eye Research, 2006
Cataract is a multifactorial disease, and a large variety of stressors induce cataracts. Many cataractogenic stressors and endoplasmic reticulum (ER) stressors induce the unfolded protein response (UPR) in various cell types. The UPR is known to produce reactive oxygen species (ROS) prior to the inducement of apoptosis.
Kengo, Ikesugi, Ryoko, Yamamoto, Michael L, Mulhern, Toshimichi, Shinohara   +3 more
openaire   +2 more sources

The unfolded protein response (UPR) pathway: the unsung hero in breast cancer management

Apoptosis, 2022
Tumor cells always have the need to produce an increased amount of proteins in the cells. This elevated amount of proteins increases the pressure on the organelles of the cell such as the endoplasmic reticulum and compels it to increase its protein folding efficiency. However, it is by a matter of fact, that the amount of proteins synthesized outweighs
Arunita, Patra, Arghya, Adhikary, Swatilekha, Ghosh   +2 more
openaire   +2 more sources

Induction of the unfolded protein response (UPR) during pseudorabies virus infection

Veterinary Microbiology, 2019
Pseudorabies virus (PRV) infection causes great economic losses in the pig industry. By disrupting the homeostasis of the endoplasmic reticulum (ER), many viral infections induce ER stress and trigger the unfolded protein response (UPR). However, the roles of ER stress and UPR in PRV infection remain unclear.
Songbai, Yang, Jingjing, Zhu, Xiaolong, Zhou, Han, Wang, Xiangchen, Li, Ayong, Zhao   +5 more
openaire   +2 more sources