Results 241 to 250 of about 67,514 (293)

Dual Role of MtHAC‐1 in Regulating Cellulase and Xylanase Production in Myceliophthora thermophila

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
Through a combination of gene deletion, overexpression analyses, and electrophoretic mobility shift assays, we demonstrate that MtHac‐1 acts as a dual‐function regulator of cellulase and xylanase production, directly modulating the expression of major cellulase and xylanase genes, as well as the regulatory gene Mtxyr1, through promoter binding ...
Yapeng Lai, Juan Wang, Ning Xie, Gang Liu, Donnabella C. Lacap‐Bugler   +4 more
wiley   +1 more source

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

Molecular and Cellular Biology, 2003
Ann-Hwee Lee, N. Iwakoshi, L. Glimcher
semanticscholar   +1 more source

Obesity‐Induced Loss of Function of Bone Marrow Mesenchymal Stromal Cells Is Linked to Cellular Stress and Irreversible at Advanced Stages

Journal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Obesity increases the likelihood of metabolic diseases and can affect stem cell function negatively. Here, we aimed to elucidate the mechanisms involved in the loss of stem cell function induced by obesity by assessing levels of oxidative stress (OS) and endoplasmic reticulum stress (ERS) in bone marrow‐derived mesenchymal stromal cells (BM ...
Ece Gizem Polat, Mehmet Emin Şeker, Burcu Pervin, Barış Ulum, Fatima Aerts‐Kaya   +4 more
wiley   +1 more source

Impact of stimulant biopolymers on the UPR (Unfolded Protein Response) induction involved in protein homeostasis in wheat : Use of the molecular marker TabZIP60s [PDF]

Dupont Maxime
openalex  

The Tacrine‐Induced Endoplasmic Reticulum Stress in AChE‐Expressed Cells Leads to Improper Assembly and Transport of the Oligomeric Enzyme: Reversal by Trehalose

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
Acetylcholinesterase (AChE) inhibitors are a class of drugs to treat Alzheimer's disease (AD). Our study reveals that some AChE inhibitors, for example, tacrine, disrupt the proper assembly and transport of oligomeric forms of AChE, resulting in endoplasmic reticulum (ER) stress. The ER stress ultimately leads to cell apoptosis. This tacrine‐induced ER
Xiaoyang Wang, Yingjie Xia, Maggie Suisui Guo, Jiahui Wu, Ajiaikebaier Dilidaer, Jin Gao, Tina Tingxia Dong, Yue Zhu, Karl Wah Keung Tsim   +8 more
wiley   +1 more source

Matching maternal and paternal experiences underpin molecular thermal acclimation

Molecular Ecology, Volume 34, Issue 15, August 2025.
Abstract The environment experienced by one generation has the potential to affect the subsequent one through non‐genetic inheritance of parental effects. Since both mothers and fathers can influence their offspring, questions arise regarding how the maternal, paternal and offspring experiences integrate into the resulting phenotype.
L. C. Bonzi, J. M. Donelson, R. K. Spinks, P. L. Munday, T. Ravasi, C. Schunter   +5 more
wiley   +1 more source

Interplay between Redox Signaling, Oxidative Stress, and Unfolded Protein Response (UPR) in Pathogenesis of Human Diseases. [PDF]

Oxid Med Cell Longev, 2019
Poplawski T, Pytel D, Dziadek J, Majsterek I.   +3 more
europepmc   +1 more source

A Holistic Investigation of Arabidopsis Proteomes Altered in Chloroplast Biogenesis and Retrograde Signalling Identifies PsbO as a Key Regulator of Chloroplast Quality Control

Plant, Cell &Environment, Volume 48, Issue 8, Page 6373-6396, August 2025.
ABSTRACT Communication between the diverse compartments of plant cells relies on an intricate network of molecular interactions that orchestrate organellar development and adaptation to environmental conditions. Plastid‐to‐nucleus signalling pathways play a key role in relaying information from developing, mature, and damaged or disintegrating ...
Dario Di Silvestre, Nicolaj Jeran, Guido Domingo, Candida Vannini, Milena Marsoni, Stefania Fortunato, Maria Concetta de Pinto, Alberto Tamborrino, Yuri Luca Negroni, Michela Zottini, Lien Tran Hong, Andrea Lomagno, Pierluigi Mauri, Paolo Pesaresi, Luca Tadini   +14 more
wiley   +1 more source

Palmitate induces endoplasmic reticulum (ER) stress and activates unfolded protein response (UPR) signaling in meniscus cells [PDF]

, 2015
Raghunatha R. Yammani
openalex   +1 more source

Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex. [PDF]

Sci Rep, 2018
Jung KW, Lee KT, Averette AF, Hoy MJ, Everitt J, Heitman J, Bahn YS.   +6 more
europepmc   +1 more source