Results 121 to 130 of about 128,740 (303)
O Pacto pela Saúde e o processo de regionalização no estado de Mato Grosso
A regionalização da saúde no estado de Mato Grosso iniciou-se nos anos 1990. Neste trabalho, analisou-se a atuação da Secretaria de Estado de Saúde, no período de 2006 a 2011, mediante as dimensões: institucionalidade, governança e impactos da ...
Nereide Lúcia Martinelli +2 more
doaj +1 more source
Profile of general hospitals in the Unified Health System
Laura de Almeida Botega +2 more
openaire +5 more sources
General Data Protection Law: Unified Health System challenge
A Lei Geral de Proteção de Dados (LGPD) promulgada no Brasil em 2018 é reflxo do movimento internacional de busca pela preservação de direitos fundamentais como privacidade, intimidade, honra, direito de imagem e dignidade humana. O objetivo do estudo foi o de apontar em que medida a estrutura do sistema público de saúde brasileiro será impactada pela ...
Aragão, Suéllyn Mattos de +1 more
openaire +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Motivational Interviewing and Oral Heath: what the evidence says.
Beatriz Carriconde Colvara +1 more
doaj +1 more source

