Results 81 to 90 of about 144,849 (258)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Gasto Público em Saúde na Bahia: explorando indícios de desigualdades

open access: yesSaúde em Debate
RESUMO O artigo analisa os gastos públicos com o Sistema Único de Saúde em municípios, regiões e macrorregiões da Bahia, de 2009 a 2012. Os dados foram analisados com o auxílio do modelo de Contas Nacionais de Saúde.
Andrei Souza Teles   +2 more
doaj   +1 more source

Socioeconomic inequities in prostate cancer care: private versus public treatment settings pose a significant impact on overall survival [PDF]

open access: yesEinstein (São Paulo)
Objective To evaluate the impact of assistance from public and private health systems on the overall survival of patients with metastatic prostate cancer. Methods A total of 213 patients with metastatic prostate cancer treated at the A.C.
Amanda Caroline de Souza Costa   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pregnancy complications in Brazilian puerperal women treated in the public and private health systems

open access: yesRevista Latino-Americana de Enfermagem, 2018
Objective: to analyze the prevalence of pregnancy complications and sociodemographic profile of puerperal patients with complications, according to the form of financing of the childbirth service.
Patrícia Louise Rodrigues Varela   +3 more
doaj   +1 more source

Profile of general hospitals in the Unified Health System

open access: yesRevista de Saúde Pública, 2020
Laura de Almeida Botega   +2 more
openaire   +5 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Methodological innovation in the teaching-service integration at the medical education

open access: yesMedicina, 2016
Medical schools are seeking new scenarios of teaching and learning, taking into account the principles of the Unified Health System (SUS) and the National Curriculum Guidelines.
Maria Cristina A. de Souza   +5 more
doaj   +1 more source

Children's Hearing Health Panorama in the Unified Health System in the state of Sergipe

open access: yesCoDAS
ABSTRACT Purpose To describe the panorama of children’s hearing health in the Unified Health System of the state of Sergipe. Methods A quantitative and retrospective study consisting of four steps: 1) Search the National Registry of Health Establishments of institutions affiliated to the Health Unic System in the state of Sergipe that perform obstetric
Josilene Luciene Duarte   +6 more
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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