Results 81 to 90 of about 1,152,162 (330)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Monitoring System Building Plan for Risk of Civil Office [PDF]

, 2020
The development of increasingly rapid information technology requires companies to have a system that is able to provide data and information quickly and accurately.
Faris, M. R. (Muhammad), Pane, A. R. (Asni), Rahayu, S. (Sri)   +2 more
core  

Schedulability Analysis for Rate Monotonic Algorithm-Shortest Job First Using UML-RT

Modelling and Simulation in Engineering, 2014
System modelling with a unified modelling language (UML) is an active research area for developing real-time system development. UML is widely used modelling language in software engineering community, to specify the requirement, and analyse the target ...
S. Ewins Pon Pushpa, Manamalli Devasikamani   +1 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Unified modeling language code generation from diagram images using multimodal large language models

Machine Learning with Applications
The Unified Modeling Language is a standardized visual language widely used for modeling and documenting the design of software systems. Although many tools are available that generate UML diagrams from UML code, generating executable UML code from image-
Averi Bates, Ryan Vavricka, Shane Carleton, Ruosi Shao, Chongle Pan   +4 more
doaj   +1 more source

A Unified Modeling Language-Based Design And Application For A Library Management Information System

, 2014
This paper firstly introduces the main content of the Unified Modeling Language (UML) and proves that it can transmit information among the users, the developers, the designers and the managers efficiently, which improves their collaboration capabilities
J. Zheng, Yunqing Feng, Yun Zhao
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

A Metamodel for the Unified Modeling Language [PDF]

, 2004
Nowadays models, rather than code, become the key artifacts of software development. Consequently, this raises the level of requirements for modeling languages on which modeling practitioners should rely in their work. A minor inconsistency of a modeling
Naumenko, Andrey, Wegmann, Alain
core