Results 51 to 60 of about 1,481,194 (295)
On the convergence of multidimensional S-fractions with independent variables
Karpatsʹkì Matematičnì Publìkacìï, 2018 In this paper, we investigate the convergence of multidimensional S-fractions with independent variables, which are a multidimensional generalization of S-fractions.
O.S. Bodnar, R.I. Dmytryshyn
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Topological convergence and uniform convergence [PDF]
Czechoslovak Mathematical Journal, 1987 For uniform spaces X and Y the author studies the following convergences on the set of all mappings from X to Y: Uniform convergence, uniform convergence on compacta, pointwise convergence, Hausdorff convergence, Leader convergence, topological convergence and proximal convergence.
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Advances in Difference Equations, 2017 In this paper, we consider a singularly perturbed reaction-diffusion problem with a discontinuous source term. Boundary and interior layers appear in the solution.
Zhongdi Cen, Anbo Le, Aimin Xu
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Local Linear Fitting Under Near Epoch Dependence: Uniform consistency with Convergence Rates [PDF]
Local linear fitting is a popular nonparametric method in statistical and econometric modelling. Lu and Linton (2007) established the pointwise asymptotic distribution for the local linear estimator of a nonparametric regression function under the ...
Zudi Lu, Degui Li, Oliver Linton
core
Uniform Convergence of Translation Operators
Advances in Pure Mathematics, 2022 20 ...
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source