Results 71 to 80 of about 4,221,495 (320)

Numerical treatment for the solution of singularly perturbed pseudo-parabolic problem on an equidistributed grid

open access: yesNonlinear Engineering, 2020
The initial-boundary value problem for a pseudo-parabolic equation exhibiting initial layer is considered. For solving this problem numerically independence of the perturbation parameter, we propose a difference scheme which consists of the implicit ...
Mohapatra Jugal, Shakti Deepti
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Topologies between compact and uniform convergence on function spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1993
This paper studies two topologies on the set of all continuous real-valued functions on a Tychonoff space which lie between the topologies of compact convergence and uniform convergence.
S. Kundu, R. A. McCoy
doaj   +1 more source

On the convergence of multidimensional S-fractions with independent variables

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2018
In this paper, we investigate the convergence of multidimensional S-fractions with independent variables, which are a multidimensional generalization of S-fractions.
O.S. Bodnar, R.I. Dmytryshyn
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Statistically Relatively Uniform Convergence of Positive Linear Operators

open access: yes, 2016
In this paper we define a new type of statistical convergence by using the notions of the natural density and the relatively uniform convergence. We study its use in the Korovkin-type approximation theory.
K. Demirci, S. Orhan
semanticscholar   +1 more source

Topological convergence and uniform convergence [PDF]

open access: yesCzechoslovak Mathematical Journal, 1987
For uniform spaces X and Y the author studies the following convergences on the set of all mappings from X to Y: Uniform convergence, uniform convergence on compacta, pointwise convergence, Hausdorff convergence, Leader convergence, topological convergence and proximal convergence.
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Uniform Convergence of Translation Operators

open access: yesAdvances in Pure Mathematics, 2022
20 ...
openaire   +2 more sources

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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