Results 61 to 70 of about 4,221,495 (320)

Uniform convergence of multiplier convergent series

Proyecciones (Antofagasta), 2017
If λ is a sequence K-space and Σ xj is a series in a topological vector space X, the series is said to be λ-multiplier convergent if the series converges in X for every t = {tj} ∈ λ. We show that if λ satisfies a gliding hump condition, called the signed strong gliding hump condition, then the series converge uniformly for t = {tj} belonging to ...
openaire   +3 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Uniform convergence on classes of subsets [PDF]

In the study of uniform convergence, one is led naturally to the question of how uniform convergence on subsets relates to uniform convergence on the whole space. This paper develops theorems on how pointwise convergence relates to uniform convergence on
Shiflett, Ray Calvin
core   +6 more sources

The Alexandroff property and the preservation of strong uniform continuity

Applied General Topology, 2010
In this paper we extend the theory of strong uniform continuity and strong uniform convergence, developed in the setting of metric spaces in, to the uniform space setting, where again the notion of shields plays a key role.
Gerald Beer
doaj   +1 more source

Influence of Tunnel Excavation on the Deformation of a Frame Building

Buildings, 2023
Tunnel excavation inevitably causes surface deformation. In urban areas, surface deformation could lead to the deformation of surrounding buildings, which may cause damage to communities when accumulated to a certain extent.
Yang Li, Guangyi Zhou, Tianjiao Li, Chun’an Tang, Bin Gong, Kaikai Wang   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Darboux-Integrability and Uniform Convergence

Real Analysis Exchange, 2004
A concept of Darboux-integrability for Banach space-valued functions defined on a basic space \((\Omega, {\mathcal D}, \mu)\) is introduced. In the finite-dimensional case for functions on \([a,b]\) this concept generalizes the Riemann integral, but in the infinite-dimensional case the Darboux-integral is more restrictive than the standard definition ...
openaire   +3 more sources

Kernel convergence of hyperbolic components. [PDF]

, 1997
We study families $G(\lambda,\cdot)$ of entire functions that are approximated by a sequence of families $G_n(\lambda,\cdot)$ of entire functions, where $\lambda\in\C$ is a parameter.
Krauskopf, B., BERND KRAUSKOPF, Kriete, H., Kriete, H, Krauskopf, B, HARTJE KRIETE   +5 more
core   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source