Results 41 to 50 of about 248,819 (194)

Metodologías para el diseño de ontologías Web = Web ontologies design methodologies

open access: yesInformación, Cultura y Sociedad, 2018
El artículo analiza las características de las ontologías Web, junto con su definición, su constitución y las tecnologías que se adoptan para su diseño e implementación en el marco de la Web Semántica.
Elsa E. Barber   +6 more
doaj  

Directions for the development of information and methodological support for industrial complex enterprises based on the uniform digital platform of the RF «Gostech»

open access: yesVestnik of Samara University. Economics and Management
The article presents the directions for the development of information and methodological support (IMS) for the activities of industrial enterprises on the basis of the unified digital platform "RosTech", which are of particular importance in the organization of innovative activities at the present stage, carried out in conditions of geoplastic ...
Nikolay M. Tyukavkin   +2 more
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A policy relevant assessment of the environmental impacts of organic farming [PDF]

open access: yes, 2000
Organic farming has become an important aspect of European agri-environmental policy. Since the implementation of EC Reg. 2078/92, the EU promotes organic farming based explicitly on its positive effects on the environment. The objective of this paper is
Dabbert, S.   +3 more
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Current problems of regulating civic participation in ensuring public safety

open access: yesМуниципалитет: экономика и управление
Introduction. The relevance of the research topic is due to the need to identify problems that hinder the integrated development of civic participation (including volunteers) in ensuring public safety, as well as a mechanism for their solution.
Aleksey M. Voronov, Artem V. Mazein
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Implementing Scientific and Technological Territorial Potential Through Interregional Integration Based on the “Smart” Specialization Approach

open access: yesУправленческое консультирование
Relevance and objectives of the research. Regional scientific and technological potential can be revealed and fully realized only taking into account the possibilities of interregional partnership and cooperation and provided that the priorities of ...
L. A. Gamidullayeva
doaj   +1 more source

International Literature Review for the Commission on Local Taxation [PDF]

open access: yes, 2015
No abstract ...
Christie, Linda, Gibb, Kenneth
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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