Results 51 to 60 of about 25,165 (253)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Управленческое консультированиеRelevance and objectives of the research. Regional scientific and technological potential can be revealed and fully realized only taking into account the possibilities of interregional partnership and cooperation and provided that the priorities of ...
L. A. Gamidullayeva
doaj +1 more source
Logical Structure of Data Base for Materials Management in Housing Construction Companies
, 1986 The author analyses the problem of designing a logical structure for data base to be used in housing construction companies. The solutions proposed in the article concern a certain group of such companies, which are linked by a common production ...
Idzikowska, Gabriela M. +1 more
core
La contextualización del mcer en la formación de profesores de idiomas en la UO
, 2021 This research aims at socializing the experiences derived from the contextualization of the Common European Frame Reference in the training of language teachers at Oriente University, and in achieving a better preparation of them, both in English and ...
Jiménez Álvarez, Marisela +3 more
core
PLoS Computational BiologyMicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally. In animals, this regulation is achieved via base-pairing with partially complementary sequences on mainly 3' UTR region of messenger RNAs (mRNAs ...
Efrat Cohen-Davidi +1 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Epidemiology, Biostatistics and Public HealthIntroduction A key methodological challenge in epidemiological studies using a cluster analysis approach is the choice of an appropriate set of controls.
Rossana Di Staso , Emilio Gianicolo
doaj +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Traditional Healers and Mental Health in Nepal: A Scoping Review [PDF]
, 2019 © 2020, Springer Science+Business Media, LLC, part of Springer Nature. Despite extensive ethnographic and qualitative research on traditional healers in Nepal, the role of traditional healers in relation to mental health has not been synthesized.
Lauren Franz +16 more
core +1 more source
A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source