Results 41 to 50 of about 1,620,241 (297)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

UNIFORMES PARA áREAS DE ALIMENTOS Y BEBIDAS [PDF]

open access: yes, 2015
Sólo visión ...
Mejia Castillo Sonia Edith
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Os Uniformes Militares Portugueses na Regeneração 1851-1892 [PDF]

open access: yes, 1998
historiografia militar em Portugal careceu durante muitos anos da abordagem científica das características que envolvem o complexo mundo dos uniformes militares.
Veludo, Sérgio
core  

Search and Discovery Tools for Astronomical On-line Resources and Services [PDF]

open access: yes, 2000
A growing number of astronomical resources and data or information services are made available through the Internet. However valuable information is frequently hidden in a deluge of non-pertinent or non up-to-date documents.
Egret, Daniel   +2 more
core   +2 more sources

Uniformization of quasi-uniform spaces [PDF]

open access: yesBulletin of the Australian Mathematical Society, 1981
This paper considers the question of when a quasi-uniform space has a compatible uniform structure. Typical of the sufficient conditions provided is the result that a quasi-uniform space whose conjugate topology is compact and R0 is uniformizable.
Raghavan, T. G., Reilly, I. L.
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Versión 1993 de los requerimientos uniformes de publicación

open access: yesBiomédica: revista del Instituto Nacional de Salud, 1994
A mediados de este ano, el lnternational Committee of Medical Journal Editors publicó una quinta versión de los requerimientos uniformes para someter manuscritos (1).
A. Loría, R. Lisker
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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