Results 91 to 100 of about 43,090 (300)

Eligibility and Endpoints for Clinical Trials in Trimodality Therapy for Bladder Cancer

Bladder Cancer
BACKGROUND: Trimodality therapy (TMT) is a viable option for muscle-invasive localized bladder cancer, providing an alternative to radical cystectomy in properly selected patients.
Parminder Singh, Leslie Ballas, Guru P. Sonpavde, Ronald C. Chen, Rick Bangs, Brian C. Bauman, Himanshu Nagar, Scott E. Delacroix, Seth P. Lerner, Jason A. Efstathiou   +9 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

UTLIZATION OF UNIFORMITY TRIALS TO ESTIMATE THE OPTIMUM PLOT SIZE AND SHAPE AND THE NUMBER OF REPLICATIONS IN MAIZE YIELD TRIALS [PDF]

Egyptian Journal of Agricultural Sciences, 2013
W. Fares, H. Fateh, Sh. Shaboon
doaj   +1 more source

Integrated analysis of key parameters in the design of a gravity-fed subsurface drip irrigation system under low pressure for predominantly sandy soil

Agricultural Water Management
Gravity-fed subsurface drip irrigation (GSDI) supplies water directly to the root zone without the need for pumping, which makes it particularly suitable for areas with limited energy access.
Eric Kakanda Tshitende, Pierre M. Kabuya, Paul Malumba, Joost Wellens   +3 more
doaj   +1 more source

Plot size and number of replicates in times of sowing and cuts of millet

Revista Brasileira de Engenharia Agrícola e Ambiental, 2016
The objective of this study was to determine the optimum plot size (Xo) and number of replicates to evaluate millet shoot fresh matter in times of sowing and cuts.
Cláudia Burin, Alberto Cargnelutti Filho, Bruna M. Alves, Marcos Toebe, Jéssica A. Kleinpaul   +4 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A criticism of the traditional analysis of banking competition [PDF]

Revised by 78 ...
Dale Osborne, Jeanne Wendel
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Spacing uniformity - Yield effects and in-field measurement

, 1996
Trials were done to investigate the effects of spacing uniformity on crop yield, and to assess a method of measuring spacing uniformity without the need to calculate the coefficient of variation.
Stephen Corkrey (14734306), Beattie, B (15506069), Fennell, JFM (15506072), John McPhee (14744095)   +3 more
core  

Biomarkers for predicting immunotherapy response and resistance in glioblastoma

Frontiers in Immunology
Glioblastoma is the most common and aggressive primary brain tumor in adults that fails to meet survival endpoint criteria in current immunotherapy Phase III clinical trials.
Samuel Kim, Matthew Abikenari, Brandon Bergsneider, Lily H. Kim, Michael Lim   +4 more
doaj   +1 more source