Results 71 to 80 of about 12,490 (237)
PLoS ONE, 2019 We propose a strategy to counteract the salt-driven disassembly of multiliposomal complexes made by electrostatic co-assembly of anionic small unilamellar liposomes and cationic star-shaped polyelectrolytes (made of quaternized poly(dimethylaminoethyl ...
Camille E Pinguet +9 more
doaj +1 more source
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, EarlyView.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Near‐Infrared Triggered Anion Transport Induces Cancer Cell Death
Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.Photo‐responsive transmembrane anion transporters that are activated with NIR light are reported. Experiments in cancer cells revealed that NIR activation of the ionophore triggered near‐IR light‐dependent chloride influx and triggered cell death. Abstract Artificial transmembrane anion carriers have shown potential in biological research and medicine,
Manzoor Ahmad +3 more
wiley +2 more sources
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler +7 more
wiley +1 more source
Small, EarlyView.Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi +13 more
wiley +1 more source
Effect of the Incorporation of Functionalized Cyclodextrins in the Liposomal Bilayer
Molecules, 2019 Liposomes loaded with drug–cyclodextrin complexes are widely used as drug delivery systems, especially for species with low aqueous solubility and stability. Investigation of the intimate interactions of macrocycles with liposomes are essential for
Romina Zappacosta +6 more
doaj +1 more source
Preparation of submicron unilamellar liposomes by freeze-drying double emulsions
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2006 A novel method is described for the preparation of sterile submicron unilamellar liposomes. The method is based on the lyophilization of double emulsions containing disaccharides as lyoprotectants in both the inner and outer aqueous phase. Using various phospholipids or mixtures of lipids as emulsifiers, the double emulsions can be prepared by a two ...
Wang, Ting +5 more
openaire +2 more sources
Leveraging Viscosity to Unlock the Osteogenic Potential of BMP‐2 Mimetic DWIVA
Small, EarlyView.Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP‐2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that the viscous properties of the cellular microenvironment play a crucial role in the mechanosensitive regulation of growth factor activity.
Finlay Cunniffe +5 more
wiley +1 more source
Transmembrane Transport of cAMP and AMP Using a Two Component Small Molecule Transport System
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.Transmembrane transport of the nucleotides cAMP (cyclic adenosine monophosphate) and AMP (adenosine monophosphate) is challenging, but can be achieved using a two‐component system consisting of a synthetic anionophore (e.g., squaramides) and a lipophilic thymine derivative.
Uththara M.C. Rathnaweera +7 more
wiley +2 more sources
Solvent‐Mediated Dewetting Principles for Cell‐Sized Liposome Formation
Small, EarlyView.Dynamics of solvent‐mediated dewetting for giant unilamellar liposome formation. Solvent removal, through changing lipid packing and membrane tension, is shown to induce partial dewetting into equilibrium low and high budding angle morphologies. Complete dewetting requires mechanical force, quantified using optical tweezers.
Mostafa Bakouei +6 more
wiley +1 more source