Results 91 to 100 of about 151,969 (265)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Use of massive parallel pyrosequencing for near full-length characterization of a unique HIV type 1 BF recombinant associated with a fatal primary infection

, 2009
Near full length genome characterization of a BF recombinant from a patient who died from multiorgan failure during HIV-1 seroconversion is reported. Massive parallel pyrosequencing was used with the shotgun approach.
Narciso, Pasquale, Bruselles, Alessandro, Prosperi, Mattia, Barbara Bartolini, Franca Del Nonno, Mattia Prosperi, Bartolini, Barbara, Isabella Abbate, Del Nonno, Franca, Maria R. Capobianchi, Alessandro Bruselles, Abbate, Isabella, Gabriella Rozera, Capobianchi, Maria R., Rozera, Gabriella, Pasquale Narciso   +15 more
core   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Advances in HIV-1 genotyping and molecular epidemiology research

Guangxi Yike Daxue xuebao
Human immunodeficiency virus type 1 (HIV-1) exhibits high genetic variability, having evolved into nine subtypes, hundreds of circulating recombinant forms (CRFs), and a series of unique recombinant forms (URFs).
ZHANG Fei, LIANG Bingyu, JIANG Junjun, YE Li, LIANG Hao   +4 more
doaj   +1 more source

Genetic organization of unique recombinant forms obtained by NGS.

, 2015
Nine unique recombinants are shown with the legend at the bottom indicating the classification of each sub-genomic fragment. Genomic coordinates for each recombination breakpoint are described in detail in the Supplemental information.
John Hackett Jr (138232), Catherine A. Brennan (829735), Michael G. Berg (829733), Beniwende Kabre (408012), Scot Federman (829734), Dora Mbanya (80741), Charles Y. Chiu (123228), Samia N. Naccache (408011), Ka-Cheung Luk (138220), Lazare Kaptué (5665927)   +9 more
core   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Emergence of HIV-1 CRF01AE/B unique recombinant forms in Kuala Lumpur, Malaysia

, 2005
Objectives: To investigate the molecular epidemiology of HIV-1 and to screen for the emergence of intersubtype recombinants in Kuala Lumpur, Malaysia. Design: A molecular epidemiology study was conducted among HIV-1 seropositive patients attending the ...
Tee, K.K., Ng, K.P., Pon, C.K., Kamarulzaman, A.   +3 more
core  

Maximum-likelihood phylogenetic analyses of 12 BF1 recombinant sequences from the Northern region.

, 2019
BF1 here identified (depicted in red) are shown together with all Brazilian BF unique recombinant forms/URFs and BF circulating recombinant forms/CRF sequences available in the Los Alamos HIV Database.
Gonzalo Bello (138839), Myuki Alfaia Esashika Crispim (7359464), Mariane Martins Araújo Stefani (4117048), Mônica Nogueira da Guarda Reis (4117045), Dagmar Kiesslich (7359470), Claudia Abrahim (7359467), Nelson Fraiji (3750997)   +6 more
core   +1 more source

Structure and stability of recombinant bovine odorant-binding protein: II. Unfolding of the monomeric forms [PDF]

, 2015
In a family of monomeric odorant-binding proteins (OBPs), bovine OBP (bOBP), that lacks conserved disulfide bond found in other OBPs, occupies unique niche because of its ability to form domain-swapped dimers.
Turoverov, Konstantin K., Irina M. Kuznetsova, Olga V. Stepanenko, Denis O. Roginskii, Stepanenko, Olesya V., Kuznetsova, Irina M., Olga V Stepanenko, Olesya V Stepanenko, Olesya V. Stepanenko, Vladimir N. Uversky, Stepanenko, Olga V., Denis O Roginskii, Konstantin K Turoverov, Uversky, Vladimir N., Roginski, Denis O., Konstantin K. Turoverov, Irina M Kuznetsova, Roginskii, Denis O., Vladimir N Uversky   +18 more
core   +1 more source