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AIDS Research and Human RetrovirusesAlthough HIV-1 infection has now become a treatable chronic condition and not the deadly illness it once was, the costs of that treatment are substantial, and each infection prevented saves both financial and other costs. In China, the most predominant subtypes are CRF07_BC, CRF01_AE, and CRF55_01B, and the various second-generation recombinants are ...
Huan Li +9 more
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AIDS Research and Human Retroviruses
Continuous recombination and variation during replication could lead to rapid evolution and genetic diversity of HIV-1. Some studies had identified that it was easy to develop new recombinant strains of HIV-1 among the populations of men who have sex with men (MSM).
Xiang Gao +11 more
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Continuous recombination and variation during replication could lead to rapid evolution and genetic diversity of HIV-1. Some studies had identified that it was easy to develop new recombinant strains of HIV-1 among the populations of men who have sex with men (MSM).
Xiang Gao +11 more
openaire +2 more sources
AIDS Research and Human Retroviruses
Yunnan Province has historically been a major gateway for the introduction of HIV-1 into China. The border region with northern Myanmar has become a significant hotspot for HIV-1 recombination. This study identified and characterized a novel circulating recombinant form (CRF) of HIV-1 in the area, designating it as CRF181_BC.
Min Chen +4 more
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Yunnan Province has historically been a major gateway for the introduction of HIV-1 into China. The border region with northern Myanmar has become a significant hotspot for HIV-1 recombination. This study identified and characterized a novel circulating recombinant form (CRF) of HIV-1 in the area, designating it as CRF181_BC.
Min Chen +4 more
openaire +2 more sources
2008
Recombination is recognized as a primary force in human immunodeficiency virus type 1 (HIV-1) evolution, increasing viral diversity through reshuffling of genomic portions. The strand-switching activity of reverse transcriptase is required to complete HIV-1 replication and can occur randomly throughout the genome, leading to viral recombination.
GALLI A. +11 more
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Recombination is recognized as a primary force in human immunodeficiency virus type 1 (HIV-1) evolution, increasing viral diversity through reshuffling of genomic portions. The strand-switching activity of reverse transcriptase is required to complete HIV-1 replication and can occur randomly throughout the genome, leading to viral recombination.
GALLI A. +11 more
openaire +2 more sources