Results 51 to 60 of about 151,969 (265)
The changing molecular epidemiology of HIV-1 in Liangshan prefecture, China, in 2021–2023
Frontiers in MicrobiologyIntroductionLiangshan Prefecture is one of the areas in China most severely affected by human immunodeficiency virus (HIV), but little is known about the molecular epidemiology of HIV-1 in this area.
Rong Pei +13 more
doaj +1 more source
Molecular epidemiology and HIV-1 variant evolution in Poland between 2015 and 2019
Scientific Reports, 2021 The occurrence of HIV-1 subtypes differs worldwide and within Europe, with non-B variants mainly found across different exposure groups. In this study, we investigated the distribution and temporal trends in HIV-1 subtype variability across Poland ...
Karol Serwin +16 more
doaj +1 more source
Identification of a New HIV-1 BC Intersubtype Circulating Recombinant Form (CRF108_BC) in Spain
Viruses, 2021 The extraordinary genetic variability of human immunodeficiency virus type 1 (HIV-1) group M has led to the identification of 10 subtypes, 102 circulating recombinant forms (CRFs) and numerous unique recombinant forms.
Javier E. Cañada +15 more
doaj +1 more source
, 2010 Background: The apoptosis-inducing serine protease granzyme B (GrB) is an important factor contributing to lysis of target cells by cytotoxic lymphocytes.
Wels, Winfried +9 more
core +1 more source
Molecular Epidemiology of HIV-1 Subtype G in the Russian Federation
Viruses, 2019 Although HIV-1 subtype A has predominated in Russia since the end of the 20th century, other viral variants also circulate in this country. The dramatic outbreak of HIV-1 subtype G in 1988-1990 represents the origin of this variant spreading in Russia ...
Anastasia Murzakova +13 more
doaj +1 more source
Cosmetic Potential of a Recombinant 50 kDa Protein
Cosmetics, 2022 Collagen and its derivative proteins have been widely used as a major component for cosmetic formulations as a natural ingredient and moisturizer. Most commercially available collagens are animal-derived collagen type I and other forms of collagen, such ...
Nesma Aly +35 more
doaj +1 more source
Identification of an HIV-1 BG Intersubtype Recombinant Form (CRF73_BG), Partially Related to CRF14_BG, Which Is Circulating in Portugal and Spain. [PDF]
PLoS ONE, 2016 HIV-1 exhibits a characteristically high genetic diversity, with the M group, responsible for the pandemic, being classified into nine subtypes, 72 circulating recombinant forms (CRFs) and numerous unique recombinant forms (URFs).
Aurora Fernández-García +13 more
doaj +1 more source
Frontiers in Microbiology, 2022 Circulating recombinant forms (CRFs) are important components of the HIV-1 pandemic. Those derived from recombination between subtype B and subsubtype F1, with 18 reported, most of them of South American origin, are among the most diverse. In this study,
Javier E. Cañada-García +14 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Estimating HIV-1 Genetic Diversity in Brazil Through Next-Generation Sequencing
Frontiers in Microbiology, 2019 Approximately 36.7 million people were living with the human immunodeficiency virus (HIV) at the end of 2016 according to UNAIDS, representing a global prevalence rate of 0.8%.
Brunna M. Alves +10 more
doaj +1 more source