Results 91 to 100 of about 87,313 (246)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Dynamic frictional contact for elastic viscoplastic material

open access: yesElectronic Journal of Differential Equations, 2007
Using a general theory for evolution inclusions, existence and uniqueness theorems are obtained for weak solutions to a frictional dynamic contact problem for elastic visco-plastic material.
Kenneth L. Kuttler
doaj  

Uniqueness of Single Peak Solutions for a Kirchhoff Equation

open access: yesMathematics
We deal with the following singular perturbation Kirchhoff equation: −ϵ2a+ϵb∫R3|∇u|2dyΔu+Q(y)u=|u|p−1u,u∈H1(R3), where constants a,b,ϵ>0 and ...
Junhao Lv, Shichao Yi, Bo Sun
doaj   +1 more source

Endocrinology in Nepal: Unique challenges, unique solutions

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Nepal has a high prevalence of various endocrine diseases, which is a challenge for its endocrinologists. This article reviews the unique features and trends of endocrine disease, including diabetes, in Nepal. It focuses on the challenges and solutions that endocrine care providers face in the country.
openaire   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Non uniqueness and uniqueness of capillary surfaces

open access: yesManuscripta Mathematica, 1988
A capillary surface is a two dimensional surface in \({\mathbb{R}}^ 3\), whose mean curvature H(x), \(x\in {\mathbb{R}}^ 3\), \(x=(x_ 1,x_ 2,x_ 3)\), is a given function and which meets the prescribed boundary walls of the container C in a prescribed angle \(\gamma\) ; a volume constraint is also included.
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Relatively unique, or uniquely relative

open access: yes, 2019
The relativistic transformation in hyperbolic form is uniquely symmetric, invertible, and unimodular; it also uniquely preserves quadratic differences.
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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