Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Global solutions of a model of phase transitions for dissipative thermoviscoelastic materials
Electronic Journal of Differential Equations, 2013 We analyze a highly nonlinear system of partial differential equations that may be seen as a model for solidification or melting of certain viscoelastic materials subject to thermal effects; under the assumption that solid parts of the material may ...
Welington Vieira Assuncao +1 more
doaj
Uniqueness of solutions to singular p-Laplacian equations with subcritical nonlinearity
Advances in Nonlinear Analysis, 2017 We present a geometric approach to the study of quasilinear elliptic p-Laplacian problems on a ball in ℝn${\mathbb{R}^{n}}$ using techniques from dynamical systems.
Maultsby Bevin
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Existence of solutions to Burgers equations in a non-parabolic domain
Electronic Journal of Differential Equations, 2018 In this article, we study the semilinear Burgers equation with time variable coefficients, subject to boundary condition in a non-parabolic domain. Some assumptions on the boundary of the domain and on the coefficients of the equation will be imposed.
Yassine Benia, Boubaker-Khaled Sadallah
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Fièvre hémorragique à virus Ebola : Un vaccin en dose unique efficace chez le primate [PDF]
, 2003 Sylvain Baize, Vincent Deubel
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics [PDF]
, 2023 Yuan Chun Ding +19 more
openalex +1 more source