Results 141 to 150 of about 3,546,472 (360)

Uniqueness of solution in a rectangular domain of an evolution dam problem with heterogeneous coefficients

open access: yesElectronic Journal of Differential Equations, 2018
In this article, we consider an evolution dam problem with heterogeneous coefficients of type $a(x_1)(u_{x_2}+\chi)_{x_2}-\chi_t=0$ in a bounded rectangular domain of $\mathbb{R}^2$. We establish uniqueness of the solution for this problem.
Elmehdi Zaouche
doaj  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Existence and smoothness of solutions to second initial boundary value problems for Schrodinger systems in cylinders with non-smooth bases

open access: yesElectronic Journal of Differential Equations, 2008
In this paper, we consider the second initial boundary value problem for strongly general Schrodinger systems in both the finite and the infinite cylinders $Q_T ...
Nguyen Manh Hung, Nguyen Thi Kim Son
doaj  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Uniqueness logic

open access: yesTheoretical Computer Science, 2006
AbstractA uniqueness type system is used to distinguish values which are referenced at most once from values which may be referenced an arbitrary number of times in a program. Uniqueness type systems are used in the Clean and Mercury programming languages to provide efficiently updatable data-structures and I/O without compromising referential ...
openaire   +2 more sources

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