Results 81 to 90 of about 826,823 (225)
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Demonstratio Mathematica, 2019 In this paper, we establish the existence and uniqueness of solutions for a class of initial value problem for nonlinear implicit fractional differential equations with Riemann-Liouville fractional derivative, also, the stability of this class of problem.
Benchohra Mouffak +2 more
doaj +1 more source
On the uniqueness of conical K\"ahler-Einstein metrics [PDF]
, 2014 The purpose of this paper is to prove the uniqueness of conical K\"ahler-Einstein metrics, under the condition that the twisted $Ding$-functional is proper.
Li, Long
core
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Existence and uniqueness of a local solution for x' = f(t,x) using inverse functions
Electronic Journal of Differential Equations, 2013 A condition on the function $f$ is given such that the scalar ordinary differential equation $x' = f(t,x)$ with initial condition $x(t_0) = x_0$ has a unique solution in a neighborhood of $t_0$. An example illustrates that this result can be used when
Jeffrey T. Hoag
doaj
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic +2 more
wiley +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Relative Cuntz-Krieger algebras of finitely aligned higher-rank graphs [PDF]
, 2003 We define the relative Cuntz-Krieger algebras associated to finitely aligned higher-rank graphs. We prove versions of the gauge-invariant uniqueness theorem and the Cuntz-Krieger uniqueness theorem for relative Cuntz-Krieger algebras.Comment: 16 ...
Sims, Aidan
core
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Dissipative Boussinesq equations on non-cylindrical domains in R^n
Electronic Journal of Differential Equations, 2010 This article concerns the initial-boundary value problem for the nonlinear Boussinesq equations on time dependent domains in $mathbb{R}^n$ with $1leq n leq 4$.
Haroldo R. Clark +3 more
doaj