Results 81 to 90 of about 87,313 (246)

Maximum and minimum principles for nonlinear transport equations on discrete-space domains

open access: yesElectronic Journal of Differential Equations, 2014
We consider nonlinear scalar transport equations on the domain with discrete space and continuous time. As a motivation we derive a conservation law on these domains.
Jonas Volek
doaj  

On second-order linear Stieltjes differential equations with non-constant coefficients

open access: yesOpen Mathematics
In this work, we define the notions of Wronskian and simplified Wronskian for Stieltjes derivatives and study some of their properties in a similar manner to the context of time scales or the usual derivative.
Fernández Francisco J.   +2 more
doaj   +1 more source

Uniqueness of the power of meromorphic functions with its differential polynomial sharing a set [PDF]

open access: yesMathematica Moravica, 2016
This paper is devoted to the uniqueness problem of the power of a meromorphic function with its differential polynomial sharing a set. Our result will extend a number of results obtained in the theory of normal families.
Abhijit Banerjee, Bikash Chakraborty
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A nonlocal mixed semilinear problem for second-order hyperbolic equations

open access: yesElectronic Journal of Differential Equations, 2003
In this work we study a nonlinear hyperbolic one-dimensional problem with a nonlocal condition. We establish a blow up result for large initial data and a decay result for small initial data.
Said Mesloub, Salim A. Messaoudi
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Uniqueness of positive solutions to a class of semilinear elliptic equations

open access: yesBoundary Value Problems, 2011
In this article, we consider the uniqueness of positive radial solutions to the Dirichlet boundary value problem Δ u + f ( | x | , u ) + g ( | x | ) x ⋅ ∇ u = 0 , x ∈ Ω , u = 0 , x ∈ ∂ Ω ,
Li Chunming, Zhou Yong
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Existence of Solutions to a System of Fractional q-Difference Boundary Value Problems

open access: yesMathematics
We are investigating the existence of solutions to a system of two fractional q-difference equations containing fractional q-integral terms, subject to multi-point boundary conditions that encompass q-derivatives and fractional q-derivatives of different
Alexandru Tudorache, Rodica Luca
doaj   +1 more source

Endocrinology in Thailand: Unique challenges, unique solutions

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Thailand is a developing country in Southeast Asia with a nationally acknowledged requirement for improvement of the medical system. At present, endocrinology is a specific branch of medicine that is taught in few medical schools. There are very few endocrinologists in Thailand, who are unable to cope with the large number of patients with ...
openaire   +3 more sources

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