Results 41 to 50 of about 3,126,546 (267)

Exploring the effectiveness of a COVID-19 contact tracing app using an agent-based model

Scientific Reports, 2020
A contact-tracing strategy has been deemed necessary to contain the spread of COVID-19 following the relaxation of lockdown measures. Using an agent-based model, we explore one of the technology-based strategies proposed, a contact-tracing smartphone app.
Jonatan Almagor, Stefano Picascia
doaj   +1 more source

Patterns of inflammation, microstructural alterations, and sodium accumulation define multiple sclerosis subtypes after 15 years from onset

Frontiers in Neuroinformatics, 2023
IntroductionConventional MRI is routinely used for the characterization of pathological changes in multiple sclerosis (MS), but due to its lack of specificity is unable to provide accurate prognoses, explain disease heterogeneity and reconcile the gap ...
Antonio Ricciardi, Francesco Grussu, Francesco Grussu, Baris Kanber, Baris Kanber, Ferran Prados, Ferran Prados, Ferran Prados, Marios C. Yiannakas, Bhavana S. Solanky, Frank Riemer, Xavier Golay, Wallace Brownlee, Olga Ciccarelli, Olga Ciccarelli, Daniel C. Alexander, Claudia A. M. Gandini Wheeler-Kingshott, Claudia A. M. Gandini Wheeler-Kingshott, Claudia A. M. Gandini Wheeler-Kingshott   +18 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Opinion: more mouse models and more translation needed for ALS

Molecular Neurodegeneration, 2023
Amyotrophic lateral sclerosis is a complex disorder most of which is ‘sporadic’ of unknown origin but approximately 10% is familial, arising from single mutations in any of more than 30 genes.
Elizabeth M.C. Fisher, Linda Greensmith, Andrea Malaspina, Pietro Fratta, Michael G. Hanna, Giampietro Schiavo, Adrian M. Isaacs, Richard W. Orrell, Thomas J. Cunningham, Abraham Acevedo Arozena   +9 more
doaj   +1 more source

Inteligencia artificial en esclerosis múltiple

Kranion, 2023
La inteligencia artificial (IA) es la rama de la ciencia que tiene como objetivo crear algoritmos capaces de llevar a cabo tareas que normalmente requieren inteligencia humana.
Carmen Tur, Sara Collorone
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Sound power of speech between 63 Hz and 20 kHz at a normal vocal effort level

Acta Acustica
This paper reports anechoic measurements of speech (720 IEEE sentences) produced at a normal vocal effort by 12 native British English speakers (six male, six female) over a hemispherical region (1 m radius) on one side of the talker to allow calculation
Hopkins Carl, Graetzer Simone, Seiffert Gary   +2 more
doaj   +1 more source

Minimal Tilings of a Unit Square [PDF]

The College Mathematics Journal, 2017
Tile the unit square with $n$ small squares. We determine the minimum of the sum of the side lengths of the $n$ small squares, where the minimum is taken over all tilings of the unit square with $n$ squares.
openaire   +2 more sources

Møte i arbeidsgruppen for Oria 17-09-2021

, 2021
Møte i arbeidsgruppen for Oria 17-09-2021.Møte i arbeidsgruppen for Oria 17-09 ...
Unit
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source