Results 51 to 60 of about 33,565 (252)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Closed derivation on the unit square [PDF]

Bulletin of the Australian Mathematical Society, 1986
In this paper we extend Kurose's structure theorem to characterize a closed derivation in the algebra of continuous functions on the unit square, under the conditions that the range is the whole algebra and the kernel is the set of all functions depend only on the second variable, as a partial derivative with respect to signed measures on the unit ...
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Minimal Tilings of a Unit Square [PDF]

The College Mathematics Journal, 2017
Tile the unit square with $n$ small squares. We determine the minimum of the sum of the side lengths of the $n$ small squares, where the minimum is taken over all tilings of the unit square with $n$ squares.
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

An MRI assessment of mechanisms underlying lesion growth and shrinkage in multiple sclerosis

Annals of Clinical and Translational Neurology
Objective To assess the pathological mechanisms contributing to white matter (WM) lesion expansion or contraction and remyelination in multiple sclerosis (MS).
Ermelinda De Meo, Ferran Prados Carrasco, J. William L. Brown, Alasdair J. Coles, Nick G. Cunniffe, Amy E. Jolly, Baris Kanber, Rebecca Samson, Frederik Barkhof, Declan Chard   +9 more
doaj   +1 more source

Transplantation of Cryopreserved Olfactory Ensheathing Cells Restores Loss of Functions in an Experimental Model

Cell Transplantation, 2023
In the past decades, the properties of olfactory ensheathing cells (OECs) have been widely investigated. Studies have shown that transplantation of OECs cultured from the olfactory bulb mediates axonal regeneration, remyelination and restores lost ...
Kamile Minkelyte, Daqing Li, Ying Li, Ahmed Ibrahim   +3 more
doaj   +1 more source

DOUBLE COVERINGS AND UNIT SQUARE PROBLEMS FOR CYCLOTOMIC FIELDS

, 2011
In this paper, using the theory of double coverings of cyclotomic fields, we give a formula for [Formula: see text], where K = ℚ(ζn), G = Gal (K/ℚ), 𝔽2 = ℤ/2ℤ and UK is the unit group of K.
YAN LI, LIANRONG MA
core   +1 more source

The human pathogen, Schistosoma mansoni, lacks the cognate sequence for human telomerase reverse transcriptase (hTERT) and relies on the snail host, Biomphalaria glabrata homologous enzyme for its intra-molluscan development. [PDF]

, 2023
Data Availability: Data will be made available on requestSupplementary Files are available online at: https://assets-eu.researchsquare.com/files/rs-3069723/v1/0b4848eb1c2387c026138564.pdf .The human telomerase reverse transcriptase (hTERT) is the ...
Grigoriadis, D, Knight, M, Parn, S, Elhelu, O, Brindley, P, Bridger, J, Yadav, S, Mann, V, Pels, N, Rinaldi, G   +9 more
core   +1 more source

ON-LINE COVERING THE UNIT SQUARE BY SQUARES AND THE THREE-DIMENSIONAL UNIT CUBE BY CUBES

Demonstratio Mathematica, 1995
Among others the following results are proved: The unit square can be on-line covered by every sequence of squares of the total area at least \(7/4 \cdot {\root 3 \of {9}} + 13/8 \cong 5.265\). The cube \(I^3\) permits an on-line covering by every sequence of three- dimensional cubes of the total volume at least \(143/32 + 3/8 \cdot (9/2)^{3/4} + 63/8 \
Januszewski, Janusz, Lassak, Marek
openaire   +2 more sources