Results 61 to 70 of about 2,655,581 (286)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Frontiers in Neuroinformatics, 2022 Fractional anisotropy (FA) is a quantitative map sensitive to microstructural properties of tissues in vivo and it is extensively used to study the healthy and pathological brain.
Marta Gaviraghi +12 more
doaj +1 more source
Least-Squares Autoregression with Near-unit Root [PDF]
, 2000 In autoregressive models, assumptions about the initial conditions seem to matter a lot when one of the roots of the characteristic polynomial is near the unit circle. In particular, the fixed start-up model (where the first few observations are treated asymmetrically) behaves quite differently in small samples than the stationary model which assumes ...
Magnus, J.R., Rothenberg, T.J.
openaire +4 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Cell Transplantation, 2018 Trauma causes spinal cord injury, and the devastating consequences of the injury are due to the failure of the damaged central nervous system (CNS) axons to regenerate. Previous studies have shown that olfactory ensheathing cells (OECs) are a unique type
Modinat Olushanu +3 more
doaj +1 more source
Unit squares intersecting all secants of a square [PDF]
Discrete & Computational Geometry, 1994 Let S be a square of side length s > 0. We construct, for any sufficiently large s, a set of less than 1.994 s closed unit squares whose sides are parallel to those of S such that any straight line intersecting S intersects at least one square of S. It disproves L.
openaire +3 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
The influence of schizotypal traits on attention under high perceptual load
Schizophrenia Research: Cognition, 2018 Schizophrenia Spectrum Disorders (SSD) are known to be characterised by abnormalities in attentional processes, but there are inconsistencies in the literature that remain unresolved.
Hanne Stotesbury +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Specialist multidisciplinary input maximises rare disease diagnoses from whole genome sequencing
Nature Communications, 2022 Whole genome sequencing is emerging as a first-line test for rare genetic diseases. In this study, authors maximise diagnoses by supplementing existing semiautomated analyses with clinically driven reevaluation of genomic data by a specialist ...
William L. Macken +22 more
doaj +1 more source