Results 81 to 90 of about 16,187,139 (338)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Population Dynamics of the Deer Mouse (Peromyscus maniculatus) and Sin Nombre Virus, California Channel Islands

open access: yesEmerging Infectious Diseases, 1997
Hantavirus pulmonary syndrome, first documented in 1993, is caused by Sin Nombre virus (SNV), which is carried by the Peromyscus species. In 1994, high SNV antibody prevalence was identified in deer mice from two California Channel Islands.
Tim B. Graham, Bruno B. Chomel
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Knowledge-Based Patient Screening for Rare and Emerging Infectious/Parasitic Diseases: A Case Study of Brucellosis and Murine Typhus

open access: yesEmerging Infectious Diseases, 1997
Many infectious and parasitic diseases, especially those newly emerging or reemerging, present a difficult diagnostic challenge because of their obscurity and low incidence.
Craig N. Carter   +7 more
doaj   +1 more source

U.S.-EU Safe Harbor Framework; A Guide to Self-Certification [PDF]

open access: yes, 2009
[Excerpt] In this guide, we have provided an outline of the most critical pieces of the Safe Harbor Framework. The application is made available, along with a Helpful Hints Guide that explains how to fill it out.
United States Department of Commerce
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Fluoroquinolone Resistance in Neisseria gonorrhoeae

open access: yesEmerging Infectious Diseases, 1997
Fluoroquinolones and broad-spectrum cephalosporins are the most effective antimicrobial agents for the treatment of gonorrhea. However, clinically significant resistance to fluoroquinolones has emerged in Neisseria gonorrhoeae.
Joan S. Knapp   +3 more
doaj   +1 more source

Foreign service dispatches: Mozambique. LourencoMarques_1969-12-18-A131 [PDF]

open access: yes, 1969
Subject: Current Economic Development in ...
United States. Department of State.
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Asian-American Labor Force in the Recovery [PDF]

open access: yes, 2011
[Excerpt] Asian-Americans and Hawaiians and Pacific Islanders are a growing share of the United States labor market. They are also a diverse population who identify their ethnicity as Asian Indian, Chinese, Filipino, Japanese, Korean, Vietnamese and ...
United States Department of Labor
core   +1 more source

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