Results 51 to 60 of about 911,909 (305)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Girl Scouts of United States of America, 50th Anniversary, Annual Report, 1962

open access: yes, 1963
Annual report submitted by the Girl Scouts of the United States of America to Congress describing highlights from 1962, activities, organizational leadership, and other information about scouting ...
Girl Scouts of the United States of America
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A scalable system to measure contrail formation on a per-flight basis

open access: yesEnvironmental Research Communications
Persistent contrails make up a large fraction of aviation's contribution to global warming. We describe a scalable, automated detection and matching (ADM) system to determine from satellite data whether a flight has made a persistent contrail.
Scott Geraedts   +14 more
doaj   +1 more source

The effect of fatigue on balance performance in Parkinson's disease

open access: yesClinical Parkinsonism & Related Disorders, 2020
Introduction: Balance loss and falls are a common and multifactorial finding in persons with Parkinson's Disease (pwPD). Objective fatigability is thought to contribute to falls in other neurologic conditions, but its impact on balance in pwPD is not ...
Herb Karpatkin   +6 more
doaj   +1 more source

1966 Annual Report. Girl Scouts of the United States of America, 830 Third Avenue, New York, N.Y. 10022

open access: yes, 1967
Annual report submitted by the Girl Scouts of the United States of America to Congress describing highlights from 1966, activities, organizational leadership, and other information about scouting ...
Girl Scouts of the United States of America
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

United States Department of Energy Grand Junction Office Report 111(80)

open access: yes, 1980
Supplementary data for the National Uranium Resource Evaluation containing potential resource estimates in the Colorado Plateau to accompany a report on uranium in the United ...
United States. Department of Energy. Grand Junction Office.
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

85th Congress, 1st Session: Document No. 140

open access: yes, 1957
Annual report submitted by the Girl Scouts of the United States of America to Congress describing highlights from 1956, activities, finances, organizational leadership, and other information about scouting ...
Girl Scouts of the United States of America
core  

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