Results 71 to 80 of about 816 (272)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Bidirectional Privacy Preservation in Web Services

Computers
In web-based services, users are often required to submit personal data, which may be shared with third parties. Although privacy regulations mandate the disclosure of intended recipients in privacy policies, this does not fully alleviate users’ privacy ...
Sumit Kumar Paul, D. A. Knox
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Error-free message transmission in the universal composability framework [PDF]

, 2005
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2005.Includes bibliographical references (p.
Wilson, David A. (David Alexander)
core  

Universally Composable RFID Mutual Authentication

IEEE Transactions on Dependable and Secure Computing, 2015
Universally Composable (UC) framework provides the strongest security notion for designing fully trusted cryptographic protocols, and it is very challenging on applying UC security in the design of RFID mutual authentication protocols. In this paper, we formulate the necessary conditions for achieving UC secure RFID mutual authentication protocols ...
Chunhua Su, Bagus Santoso, Yingjiu Li, Robert H. Deng, Xinyi Huang 0001   +4 more
openaire   +3 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

CommTLC: An Alternative to Reduce the Attack Surface of HTLCs in Lightning Networks

IET Blockchain
The Payment Channel Network is widely recognized as one of the most effective solutions for handling off‐chain transactions and addressing blockchain scalability challenges.
Prerna Arote, Joy Kuri
doaj   +1 more source

Universal Composability is Robust Compilation

, 2020
This paper discusses the relationship between two frameworks: universal composability (UC) and robust compilation (RC). In cryptography, UC is a framework for the specification and analysis of cryptographic protocols with a strong compositionality ...
Wahby, Riad S., Künnemann, Robert, Patrignani, Marco   +2 more
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source