Results 31 to 40 of about 2,160,399 (278)

Designers and manufacturers’ perspectives on inclusive/universal design [PDF]

, 2003
Inclusive design in the U.K. and its U.S. counterpart, universal design, present opportunities and challenges to industry. In order to encourage manufacturers and design companies to adopt more inclusive design practices, the research has been carried ...
Clarkson, PJ, Dong, H, Keates, S
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Evaluating Public Participation in a Project Plan Review: A Nigerian Case Study

Journal of MultiDisciplinary Evaluation, 2020
Background:  Rooted in national and international laws regarding project planning and implementation is public participation. However, it is unclear whether public projects are enabling sufficient public input or are likely to be able to meet future ...
Adewumi I. Badiora, Abdullateef I. Bako, Daniel O. Olaleye   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Concepts of Accessibility and Equality in Design Education: The Universal Design Approach

Iconarp International Journal of Architecture and Planning, 2014
Universal design approach aims to design products and environments that provide equal access for everyone to the variety of activities. Universal design applications and research and discussions related to these applications can be seen in different ...
Guliz Mugan Akıncı
doaj   +2 more sources

UNIVERSAL DESIGN APPLICATION THROUGH SOUTH KOREA REDEVELOPMENT (A Study Review) [PDF]

, 2016
The evolution toward Universal Design was began in the 1950s with a new attention to design for people with disabilities. At the same era South Korea began their development after several wars. Recently some of researchs and projects in South Korea which
HARSRITANTO, Bangun Indrakusumo R
core  

Accessibility of Tourism Space from a Geographical Perspective [PDF]

, 2014
The accessibility of tourism space is becoming an increasingly significant issue in geographical research due to, amongst other things, demographic changes (an ageing population, growing numbers of people with disabilities) alongside guaranteeing a ...
Zajadacz, Alina
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Universal Design: Planning and Design for All [PDF]

, 1997
[Excerpt] This report attempts to develop and illustrate the concept of universal design. The aim of universal design is to develop theory, principles and solutions to enable everybody to use the same physical solutions to the greatest extent possible ...
Aslaksen, Finn, Bergh, Steinar, Bringa, Olav Rand, Heggem, Edel Kristin   +3 more
core   +1 more source

The design-by-adaptation approach to universal access: learning from videogame technology [PDF]

, 2010
This paper proposes an alternative approach to the design of universally accessible interfaces to that provided by formal design frameworks applied ab initio to the development of new software. This approach, design-byadaptation, involves the transfer of
A Dam van, A Savidis, AU Franck, B Schneiderman, C Clanton, C Jennett, C Ware, CD Wickens, D Guo, D Harris, D Joiner, EP McCormick, HM Sayers, HM Sayers, IDH Shepherd, IDH Shepherd, Iestyn D. Bleasdale-Shepherd, Ifan D. H. Shepherd, JA Jacko, JA Jacko, JM Carroll, M Hassenzahl, M Lewis, M Tory, MD Dickey, ME Hacklay, N Andrienko, P Dourish, RM Keesing, S Burigat, T Manninen, T-M Rhyne, W Kruger   +32 more
core   +1 more source