Results 131 to 140 of about 1,472,593 (206)

Cross‐Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses

European Journal of Immunology, Volume 56, Issue 10, October 2026.
In this review article, Marchand et al. compare cross ‐ and broadly ‐neutralizing human antibodies against non ‐ enveloped viruses from several major families, discussing their structural characteristics, neutralization mechanisms and relevance for the development of antiviral vaccines and therapeutics.
Sarah Marchand, Samy Taouli, Dorian McIlroy   +2 more
wiley   +1 more source

Nucleoprotein vaccine induces cross-protective cytotoxic T lymphocytes against both lineages of influenza B virus

, 2020
Purpose: The influenza B virus diverges into two antigenically distinct lineages: B/Yamagata and B/Victoria. Influenza B is the dominant circulating virus during some influenza seasons, and recent data demonstrated that influenza A and B infection ...
장준
core   +1 more source

Strategies targeting hemagglutinin cocktail as a potential universal influenza vaccine. [PDF]

Front Microbiol, 2022
Liu X, Zhao T, Wang L, Li M, Sun C, Shu Y.   +5 more
europepmc   +1 more source

The National Health and Medical Research Council Research Impact Indicators: Unveiling Omissions and Blind Spots, and Positioning for Change

Health Promotion Journal of Australia, Volume 37, Issue 4, October 2026.
ABSTRACT Issue Addressed This study assesses how the concept of (health) research impact has been operationalised in National Health and Medical Research Council (NHMRC) Impact Case Studies, and if and how lived experience research priorities have been considered, to ascertain implications for Australian health and medical research.
Nizam Abdu, Maria Unwin, Caroline Robertson, Oliver Black (Anaiwan), Victoria J. Palmer, Amanda J. Wheeler, Amanda L. Neil   +6 more
wiley   +1 more source

Identification and In Silico Characterization of a Conserved Peptide on Influenza Hemagglutinin Protein: A New Potential Antigen for Universal Influenza Vaccine Development. [PDF]

Nanomaterials (Basel), 2023
Khalaj-Hedayati A, Moosavi S, Manta O, Helal MH, Ibrahim MM, El-Bahy ZM, Supriyanto G.   +6 more
europepmc   +1 more source

Anti‐idiotypic antibodies as molecular mimics of conserved influenza hemagglutinin epitopes

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Broadly neutralizing antibodies (bNAbs) provide insights for developing universal influenza vaccines through their ability to neutralize diverse viral strains. However, designing antigens that reliably elicit bNAb responses remains challenging due to the difficulty in targeting conserved epitopes with a single antigen.
Hiroshi Itou, Kaori Sano, Akira Ainai, Kazushige Otsuki, Toshikazu Inoue, Takuya Hemmi, Hideki Hasegawa, Tadaki Suzuki   +7 more
wiley   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, Volume 183, Issue 20, Page 6225-6239, October 2026.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source

Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection

mBio
Cellular and molecular characterization of immune responses elicited by influenza virus infection and seasonal vaccination have informed efforts to improve vaccine efficacy, breadth, and longevity.
André Nicolás León, Alesandra J. Rodriguez, Sara T. Richey, Alba Torrents de la Pena, Rachael M. Wolters, Abigail M. Jackson, Katherine Webb, C. Buddy Creech, Sandra Yoder, Philip A. Mudd, James E. Crowe, Julianna Han, Andrew B. Ward   +12 more
doaj   +1 more source

Genotype II Live‐Attenuated ASFV Vaccine Bearing 24 Genes Deletion in 3 Independent Regions Is Able to Provide Complete Protection Against Homologous Lethal Challenge

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
African swine fever (ASF) is a highly contagious and lethal viral disease of swine. Therefore, it is urgent to develop a safe and effective vaccine. We constructed a live‐attenuated ASF vaccine bearing 24 gene deletions in 3 independent regions, ASFV‐Δ24.
Fan Xu, Wen Dang, Yu Du, Tao Li, Huanan Liu, Zhengwang Shi, Hong Tian, Jijun He, Haixue Zheng   +8 more
wiley   +1 more source

The Development of a Novel Broad-Spectrum Influenza Polypeptide Vaccine Based on Multi-Epitope Tandem Sequences

Vaccines
Background: Polypeptide vaccines have the potential to improve immune responses by targeting conserved and weakly immunogenic regions in antigens. This study aimed to identify and evaluate the efficacy of a novel influenza universal vaccine candidate ...
Song Zhao, Junhao Luo, Wenhui Guo, Li Li, Siyu Pu, Libo Dong, Wenfei Zhu, Rongbao Gao   +7 more
doaj   +1 more source