Results 111 to 120 of about 1,472,593 (206)

Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation

Cell Proliferation, EarlyView.
Olfactory tuft cells communicate with other mucosal cells in maintaining olfactory epithelial immunity and sensory function. Disruption of tuft cell signalling pathways causes a skewed immune response, leading to heightened inflammation and increased activation of the quiescent stem cells, which are further exacerbated by viral infection.
Sai‐Sai Zhang, Haiyan Wang, Yi‐Sen Yang, Yi‐Hong Li, Defu Yu, Yushi Yao, Ruhong Zhou, Liquan Huang   +7 more
wiley   +1 more source

Influenza Vaccine With Consensus Internal Antigens as Immunogens Provides Cross-Group Protection Against Influenza A Viruses

Frontiers in Microbiology, 2019
Given that continuing antigenic shift and drift of influenza A viruses result in the escape from previous vaccine-induced immune protection, a universal influenza vaccine has been actively sought.
Xinci Xie, Chen Zhao, Qian He, Tianyi Qiu, Songhua Yuan, Longfei Ding, Lu Liu, Lang Jiang, Jing Wang, Linxia Zhang, Chao Zhang, Xiang Wang, Dongming Zhou, Xiaoyan Zhang, Jianqing Xu   +14 more
doaj   +1 more source

Frontline Healthcare Professionals' Perceptions of the Duty to Care During the COVID‐19 Pandemic: A Multi‐Method Study in Mozambique

Developing World Bioethics, EarlyView.
ABSTRACT COVID‐19 intensified ethical tensions between clinicians' duty to care and self‐protection amid PPE shortages. We explored frontline healthcare professionals' perspectives in Maputo, Mozambique. Semi‐structured interviews with healthcare professionals at four hospitals (April–June 2022) were recorded in Portuguese, transcribed, and ...
Ângela Alface, Graça Salomé, Khátia Munguambe, Troy D. Moon, Esperança Sevene, Elizabeth Heitman   +5 more
wiley   +1 more source

Preventing infections after CD19‐directed chimeric antigen receptor T‐cell therapies for lymphoma: a consensus practice statement

Internal Medicine Journal, EarlyView.
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley, Philip George, Gemma Reynolds, Adam Stewart, Hang Quach, Nicole O'Leary, Zoe McQuilten, Andrea S. Henden, Lynette Chee, Chan Y. Cheah, Olivia Bupha‐Intr, Emily Blyth, Ben Teh, Monica Slavin, Michael Dickinson, Robert Weinkove   +15 more
wiley   +1 more source

Inactivated recombinant influenza vaccine: the promising direction for the next generation of influenza vaccine

Expert Review of Vaccines
Introduction Vaccination is the most effective method to control the prevalence of seasonal influenza and the most widely used influenza vaccine is the inactivated influenza vaccine (IIV).
Hua Shi, Ted M. Ross
doaj   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Effectiveness of an influenza vaccine programme for care home staff to prevent death, morbidity, and health service use among residents: cluster randomised controlled trial [PDF]

, 2006
Objective To determine whether vaccination of care home staff against influenza indirectly protects residents.Design Pair matched cluster randomised controlled trial.Setting Large private chain of UK care homes during the winters of 2003-4 and 2004-5 ...
Murad, S, Smedley, J, Hayward, AC, Wetten, S, Harling, R, Watson, JM, Johnson, AM, Munro, S   +7 more
core  

Networked Regional Resilience: Diffusion of Risk and Adaptation Across Interconnected Regions

Journal of Regional Science, EarlyView.
ABSTRACT Regions face not only direct exposure to economic and physical shocks but also indirect consequences of actions in interconnected regions. This paper examines how socio‐spatial networks shape regional resilience to contagious shocks through dynamic feedback between risk diffusion and adaptation diffusion.
Xiaoyi Han, Yilan Xu, Yi Huang, Linlin Fan, Minhong Xu, Song Gao   +5 more
wiley   +1 more source

Influenza vaccination uptake among people aged over 85 years: an audit of primary care practice in the UK [PDF]

, 2014
Public health research and national guidelines have advocated for seasonal influenza vaccination in the elderly. General practice has established itself as an ideal setting for the safe administration and monitoring of vaccines.1 Due to waning immune
Arnott, ND, Fitchett, JR
core  

Plant‐Derived Probiotics From Fermented Foods: Current Evidence on Antiviral Mechanisms and Gut–Lung Axis Modulation

Food Frontiers, Volume 7, Issue 6, November 2026.
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing, Yaoyuan Hu, Yingying Ma, Peng Yao, Jingjing Jiang, Jiao Guo, Shuangmei Liu   +6 more
wiley   +1 more source