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Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential Target Antigens and Critical Aspects for a Universal Influenza Vaccine. [PDF]

Cold Spring Harb Perspect Biol, 2018
Krammer F, García-Sastre A, Palese P.
europepmc   +1 more source

mRNA-1010 and the Future of Seasonal Influenza Prevention: Towards Next-Generation Respiratory Vaccination. [PDF]

Vaccines (Basel)
Panagiotopoulos AP, Tsakri D, Ranellou K, Anastassopoulou C, Tsakris A.   +4 more
europepmc   +1 more source

Towards Better Vaccines: Enhancing Benefits, Mitigating Risks. [PDF]

Vaccines (Basel)
See KC.
europepmc   +1 more source

A universal vaccine for the influenza virus

, 2023
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The influenza universe in an mRNA vaccine

Science, 2022
An mRNA–lipid nanoparticle vaccine protects animals from 20 influenza ...
Alyson A, Kelvin, Darryl, Falzarano
openaire   +2 more sources

A “universal” human influenza A vaccine

Virus Research, 2004
We have previously reported on a universal human influenza A vaccine, based on the external domain of the transmembrane viral M2-protein (M2e) [Nature Medicine 5 (1999) 1119]. M2-protein is scarcely present on the virus but is abundantly expressed on virus-infected cells.
W, Fiers, M, De Filette, A, Birkett, S, Neirynck, W, Min Jou   +4 more
exaly   +4 more sources

Conventional influenza vaccines influence the performance of a universal influenza vaccine in mice

Vaccine, 2018
Universal influenza vaccines are designed to protect against diverse strains of influenza virus. Preclinical testing of new vaccine candidates is usually done in naïve animals, despite intended use in the human population with its varied immune history including responses to previous vaccinations.
Julia Misplon, Graeme E Price, Suzanne L Epstein   +2 more
exaly   +3 more sources

Chasing Seasonal Influenza — The Need for a Universal Influenza Vaccine

New England Journal of Medicine, 2018
Chasing Seasonal Influenza As we prepare for a potentially severe influenza season, we must consider whether our current vaccines can be improved and whether longer-term, transformative vaccine approaches are needed to minimize influenza-related morbidity and mortality.
Sheena Sullivan, Anthony Fauci, Kanta Subbarao   +2 more
exaly   +3 more sources