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Mosaic Inverted Hemagglutinin Extracellular Vesicle Vaccines Elicit Protective Systemic and Mucosal Immunity against Heterosubtypic Influenza Infection. [PDF]
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The influenza universe in an mRNA vaccine
Science, 2022An mRNA–lipid nanoparticle vaccine protects animals from 20 influenza ...
Alyson A, Kelvin, Darryl, Falzarano
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A “universal” human influenza A vaccine
Virus Research, 2004We have previously reported on a universal human influenza A vaccine, based on the external domain of the transmembrane viral M2-protein (M2e) [Nature Medicine 5 (1999) 1119]. M2-protein is scarcely present on the virus but is abundantly expressed on virus-infected cells.
W, Fiers +4 more
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Conventional influenza vaccines influence the performance of a universal influenza vaccine in mice
Vaccine, 2018Universal influenza vaccines are designed to protect against diverse strains of influenza virus. Preclinical testing of new vaccine candidates is usually done in naïve animals, despite intended use in the human population with its varied immune history including responses to previous vaccinations.
Chia-Yun Lo +2 more
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M2e-based universal influenza A vaccine
Vaccine, 2009Human influenza causes substantial morbidity and mortality. Currently, licensed influenza vaccines offer satisfactory protection if they match the infecting strain, but they come with significant drawbacks. These vaccines are derived from prototype viruses, containing the hemagglutinin of influenza viruses that are likely to cause the next epidemic ...
Walter, Fiers +7 more
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