Results 181 to 190 of about 1,472,593 (206)

Research and development of universal influenza vaccines

Microbes and Infection, 2010
The continuous threat of influenza pandemics determines the urgency and necessity to develop safe and effective vaccines against divergent influenza viruses. This review describes the advancements in the research and development of universal influenza vaccines based on the relatively conserved sequences of M2e, HA, and other proteins of influenza ...
Lanying, Du, Yusen, Zhou, Shibo, Jiang
openaire   +2 more sources

Universal Influenza Vaccination and Live Attenuated Influenza Vaccination of Children

Pediatric Infectious Disease Journal, 2008
Influenza is an uncontrolled epidemic disease that is vaccine preventable. Each winter the peak of medically attended acute respiratory illness coincides with the peak of influenza virus activity. The anatomy of an urban influenza epidemic is presented highlighting the role of children in the spread of influenza.
openaire   +2 more sources

M2e-based universal influenza A vaccine

Vaccine, 2009
Human influenza causes substantial morbidity and mortality. Currently, licensed influenza vaccines offer satisfactory protection if they match the infecting strain, but they come with significant drawbacks. These vaccines are derived from prototype viruses, containing the hemagglutinin of influenza viruses that are likely to cause the next epidemic ...
Walter, Fiers, Marina, De Filette, Karim, El Bakkouri, Bert, Schepens, Kenny, Roose, Michael, Schotsaert, Ashley, Birkett, Xavier, Saelens   +7 more
openaire   +2 more sources

Toward a universal influenza vaccine

Science, 2021
Influenza The development of a universal influenza vaccine is of paramount importance because seasonal vaccines vary in terms of protection. Darricarrere et al. have now moved a universal influenza vaccine one step closer to the clinic. The authors vaccinated nonhuman primates with headless hemagglutinin-stabilized stem antigens presented on ferritin ...
openaire   +1 more source

A promising candidate for a universal influenza vaccine

The Lancet Infectious Diseases, 2023
Irina, Isakova-Sivak, Larisa, Rudenko
openaire   +2 more sources

Universal influenza vaccines are futile when benchmarked against seasonal influenza vaccines

The Lancet Infectious Diseases, 2022
Sophie A Valkenburg, Leo L M Poon
openaire   +2 more sources

A single-shot vaccine approach for the universal influenza A vaccine candidate M2e

Proceedings of the National Academy of Sciences of the United States of America, 2022
Sylvie L Alonso, Mireille H. Lahoud, Hae-Young Park   +2 more
exaly  

Is a Universal Influenza Virus Vaccine Possible?

Annual Review of Medicine, 2020
Raffael Nachbagauer, Peter Palese
exaly  

Designing multi-epitope mRNA construct as a universal influenza vaccine candidate for future epidemic/pandemic preparedness

International Journal of Biological Macromolecules, 2023
Jiawei Mao
exaly  

T Cell Immunity against Influenza: The Long Way from Animal Models Towards a Real-Life Universal Flu Vaccine

Viruses, 2021
Dennis Lapuente
exaly