Results 181 to 190 of about 50,247 (212)

The influenza universe in an mRNA vaccine

Science, 2022
An mRNA–lipid nanoparticle vaccine protects animals from 20 influenza ...
Alyson A, Kelvin, Darryl, Falzarano
openaire   +2 more sources

A “universal” human influenza A vaccine

Virus Research, 2004
We have previously reported on a universal human influenza A vaccine, based on the external domain of the transmembrane viral M2-protein (M2e) [Nature Medicine 5 (1999) 1119]. M2-protein is scarcely present on the virus but is abundantly expressed on virus-infected cells.
W, Fiers   +4 more
exaly   +4 more sources

Conventional influenza vaccines influence the performance of a universal influenza vaccine in mice

Vaccine, 2018
Universal influenza vaccines are designed to protect against diverse strains of influenza virus. Preclinical testing of new vaccine candidates is usually done in naïve animals, despite intended use in the human population with its varied immune history including responses to previous vaccinations.
Chia-Yun Lo   +2 more
exaly   +3 more sources

M2e-based universal influenza A vaccine

Vaccine, 2009
Human influenza causes substantial morbidity and mortality. Currently, licensed influenza vaccines offer satisfactory protection if they match the infecting strain, but they come with significant drawbacks. These vaccines are derived from prototype viruses, containing the hemagglutinin of influenza viruses that are likely to cause the next epidemic ...
Walter, Fiers   +7 more
openaire   +2 more sources

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