Results 151 to 160 of about 1,366,602 (255)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

A universal vaccine candidate against Plasmodium vivax malaria confers protective immunity against the three PvCSP alleles. [PDF]

Sci Rep, 2021
Gimenez AM, Salman AM, Marques RF, López-Camacho C, Harrison K, Kim YC, Janse CJ, Soares IS, Reyes-Sandoval A.   +8 more
europepmc   +1 more source

The Africa We Want: A Perspective on the African Code Against Cancer To Be Developed for Sub‐Saharan Africa

International Journal of Cancer, EarlyView.
ABSTRACT Sub‐Saharan Africa (SSA) faces a unique cancer burden, characterized by a disproportionately high mortality‐to‐incidence ratio, a large share of infection‐related cancers, and distinct environmental exposures. Implementation of national policies on primary prevention is limited, and public literacy regarding cancer risk and curability remains ...
Anthony Kityo, Phyllis Ohene‐Agyei, Felix M. Onyije, Hannah Simba, Annet Nakaganda, Denis Chopera, Kofi Mensah Nyarko, Benido Impouma, Mary Nyangasi, Blandina Mmbaga, Valerie McCormack, Cesaltina Lorenzoni, Miriam Mutebi, Joachim Schüz, Carolina Espina   +14 more
wiley   +1 more source

Deniers and Compliers: Unpacking the Heterogeneous Effectiveness of U.S. Stay‐at‐Home Mandates During the COVID‐19 Pandemic

Journal of Applied Econometrics, EarlyView.
ABSTRACT While existing work shows COVID‐19 stay‐at‐home (SAH) policies decreased mobility on average, we lack evidence regarding heterogeneity in policy effectiveness across US counties. To uncover potential heterogeneity, we implement a novel two‐stage approach.
James Sears, Sofia B. Villas‐Boas, Molly Sears, Carly Trachtman, Linlin Fan, Andrew W. Stevens   +5 more
wiley   +1 more source

The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development. [PDF]

Cells, 2022
Feng L, Gao YY, Sun M, Li ZB, Zhang Q, Yang J, Qiao C, Jin H, Feng HS, Xian YH, Qi J, Gao GF, Liu WJ, Gao FS.   +13 more
europepmc   +1 more source

Immunization and the hepatitis B virus: A view from the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) Hepatology Committee

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Hepatitis B virus (HBV) infection remains a global health challenge, with more than 250 million people chronically infected worldwide and >2000 daily deaths from HBV‐related disease. Early‐life acquisition is the primary driver of chronic infection; up to 90% of infants infected perinatally progress to chronic HBV infection compared with ...
Benno Kohlmaier, Giuseppe Indolfi, Ulrich Baumann, Cristina Gonçalves, Emmanuel Gonzales, Norman Junge, Emanuele Nicastro, Tudor Lucian Pop, Jesus Quintero, Xavier Stephenne, Bethany Tucker, Hubert Van Der Doef, Orith Waisbourd‐Zinman, Emer Fitzpatrick   +13 more
wiley   +1 more source

Influenza-Host Interplay and Strategies for Universal Vaccine Development. [PDF]

Vaccines (Basel), 2020
Hwang HS, Chang M, Kim YA.
europepmc   +1 more source

Shaping the research agenda of pediatric gastroenterology, hepatology, and nutrition: The proposal from an Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) expert group

JPGN Reports, EarlyView.
Abstract The Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) recognized the need to define research priorities and identify knowledge gaps to guide future investigations in pediatric digestive health. Following international examples, SIGENP aimed to provide a structured framework that aligns scientific innovation with ...
Carlo Agostoni, Daniele Alberti, Renata Auricchio, Maria Elisabetta Baldassarre, Osvaldo Borrelli, Matteo Bramuzzo, Teresa Capriati, Carlo Catassi, Sabrina Cenni, Marco Crocco, Salvatore Cucchiara, Luigi Dall'Oglio, Paola De Angelis, Marco Deganello Saccomani, Fabiola Di Dato, Angelo Di Giorgio, Antonella Diamanti, Valeria Dipasquale, Enrico Felici, Ruggiero Francavilla, Valentina Giorgio, Luigi Greco, Raffaele lorio, Flavio Labriola, Paolo Lionetti, Elena Lionetti, Giuseppe Maggiore, Monica Malamisura, Claudia Mandato, Antonio Marseglia, Emanuele Nicastro, Lorenzo Norsa, Salvatore Oliva, Licia Pensabene, Elena Sofia Pieri, Paolo Quitadamo, Giusy Ranucci, Sara Renzo, Claudio Romano, Silvia Salvatore, Luca Scarallo, Maria Immacolata Spagnuolo, Annamaria Staiano, Caterina Strisciuglio, Renato Tambucci, Riccardo Troncone, Pietro Vajro   +46 more
wiley   +1 more source

Molecular mechanisms linking food processing to the human gut microbiome and metabolic health: A critical review

JSFA reports, EarlyView.
Abstract Food processing can improve safety, shelf life, digestibility and sensory quality, but it can also alter the food matrix, remove microbiota‐accessible substrates and introduce additives or heat‐derived compounds that modify host–microbe interactions.
Elijah Kolawole Oladipo, Oluwatosin Tumininu Olasinde, Oluwaseyi Samuel Akinpelu, Babarinde Jesulayomi Mercy, Olakanmi Oluwakemi Deborah, Ojo Oluwalonimi Christiana, Oyeyiola Olawumi Hezekiah, Christian Chibuike Aguoru, Diovu Charles Chinedu, Anyaoha Emmanuel Obinna, Helen Onyeaka   +10 more
wiley   +1 more source

Corrigendum: Recent Progress in Recombinant Influenza Vaccine Development Toward Heterosubtypic Immune Response

Frontiers in Immunology, 2022
Mark B. Carascal, Mark B. Carascal, Rance Derrick N. Pavon, Windell L. Rivera   +3 more
doaj   +1 more source