Results 131 to 140 of about 167,277 (295)

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

In support of the universal vaccination

Journal of Family Medicine and Primary Care, 2022
openaire   +3 more sources

Mixed‐mode membrane chromatography: mechanistic‐modeling‐based optimization and scale‐up of antibody charge variant separation using a novel membrane adsorber

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Efficient manufacturing of complex biopharmaceuticals increasingly relies on innovative downstream processing strategies. Membrane chromatography offers a promising alternative to resin‐based systems by enabling high‐throughput separations at elevated flow rates. Typically used in flow‐through mode, its industrial applications range
Jan Hedrich, Rita Steigmiller, Viktor Simaev, Romas Skudas, Michael Schulte, Mathias Hafner, Christian Frech   +6 more
wiley   +1 more source

Severe acute respiratory syndrome coronavirus 2 variants-Possibility of universal vaccine design: A review. [PDF]

Comput Struct Biotechnol J, 2022
Yoon E, Kim D, Jeon H, Kwon Y, Jang Y, Kim S, Hwang KY.   +6 more
europepmc   +1 more source

Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP

The Laryngoscope, EarlyView.
ABSTRACT Objective With regulatory approval of HPV‐specific immunotherapy for recurrent respiratory papillomatosis (RRP) and growing experience with systemic bevacizumab, a management algorithm incorporating these medical treatments is warranted. Data Sources and Methods RRP Foundation (RRPF) Key Opinion Leaders offer a proposed management algorithm ...
Simon R. Best, Aaron D. Friedman, Clark A. Rosen, Robert T. Sataloff, Laura A. Matrka, H. Steven Sims, David E. Rosow, Nabil F. Saba, David G. Lott, Adam M. Klein, Ted Mau, Milan R. Amin, Kathryn A. Wikenheiser‐Brokamp, Scott M. Norberg, Kim McClellan, Geoffrey D. Young, Clint T. Allen, on behalf of the Recurrent Respiratory Papillomatosis Foundation   +17 more
wiley   +1 more source

Challenges for the development of a universal vaccine against leptospirosis revealed by the evaluation of 22 vaccine candidates. [PDF]

Front Cell Infect Microbiol, 2022
Maia MAC, Bettin EB, Barbosa LN, de Oliveira NR, Bunde TT, Pedra ACK, Rosa GA, da Rosa EEB, Seixas Neto ACP, Grassmann AA, McFadden J, Dellagostin OA, McBride AJA.   +12 more
europepmc   +1 more source

Grouped Stakeholders' Journeys: A Dynamic Social Impact Theory Perspective

Psychology &Marketing, EarlyView.
ABSTRACT While customer journey research is proliferating, acumen of the broader stakeholder journey (SJ), which addresses any stakeholder's (e.g., an employee's, supplier's, or customer's) journey with the firm, remains more nascent. In particular, understanding of the role of psychological mechanisms in shaping collective or grouped stakeholders ...
Moira K. Clark, Linda D. Hollebeek, V. Kumar, Iivi Riivits‐Arkonsuo, Yide Liu   +4 more
wiley   +1 more source

Potential of ferritin 2 as an antigen for the development of a universal vaccine for avian mites, poultry red mites, tropical fowl mites, and northern fowl mites. [PDF]

Front Vet Sci, 2023
Win SY, Murata S, Fujisawa S, Seo H, Sato J, Motai Y, Sato T, Oishi E, Taneno A, Htun LL, Bawm S, Okagawa T, Maekawa N, Konnai S, Ohashi K.   +14 more
europepmc   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Cost effectiveness of school-located influenza vaccination programs for elementary and secondary school children. [PDF]

, 2019
BackgroundStudies have noted variations in the cost-effectiveness of school-located influenza vaccination (SLIV), but little is known about how SLIV's cost-effectiveness may vary by targeted age group (e.g., elementary or secondary school students), or ...
Albertin, Christina S, Concannon, Cathleen, Goldstein, Nicolas PN, Humiston, Sharon G, Rand, Cynthia M, Schaffer, Stanley J, Szilagyi, Peter G, Yoo, Byung-Kwang   +7 more
core