Results 41 to 50 of about 1,612,376 (366)

Expression of Influenza M2e-NP Recombinant Fusion Protein in Escherichia coli BL21 (DE3) and Its Binding to Antibodies

Vaccines, 2022
The current influenza vaccines only confer protection against the circulating influenza subtypes, therefore universal vaccines are needed to prevent upcoming influenza outbreaks caused by emerging influenza subtypes. The extracellular domain of influenza
Mei Peng Tan, Noorjahan Banu Mohamed Alitheen, Wen Siang Tan, Wei Boon Yap   +3 more
doaj   +1 more source

Universal Vaccine Development Against COVID-19 and Influenza [PDF]

E3S Web of Conferences
Universal vaccines appeared as a favorable solution for the rapid mutation of viruses that cause pandemics. Sufficient immune protection, safe and efficient production methods, and low-cost funding are ideal properties for universal vaccines.
Suo Zhaotaize
doaj   +1 more source

Predictions of the emergence of vaccine-resistant hepatitis B in The Gambia using a mathematical model [PDF]

, 2000
Vaccine escape variants of hepatitis B virus (HBV) have been identified world-wide. A mathematical model of HBV transmission is used to investigate the potential pattern of emergence of such variants.
Carman, W. (William), Nokes, D. James, Wilson, J. N.   +2 more
core   +2 more sources

Pharmacoeconomic Spotlight on Rotavirus Vaccine RIX4414 (Rotarix™) in Developed Countries [PDF]

, 2012
The most common cause of severe diarrhea in infants and young children is rotavirus gastroenteritis (RVGE), which is associated with significant morbidity, healthcare resource use, and direct and indirect costs in industrialized nations.
Greg L. Plosker
core   +1 more source

bNAber: database of broadly neutralizing HIV antibodies. [PDF]

, 2013
The discovery of broadly neutralizing antibodies (bNAbs) has provided an enormous impetus to the HIV vaccine research and to entire immunology. The bNAber database at http://bNAber.org provides open, user-friendly access to detailed data on the rapidly ...
Burton, Dennis R, Butera, Sal T, Eroshkin, Alexey M, Godzik, Adam, LeBlanc, Andrew, Li, Zhanwen, Post, Kai, Rajput, Akhil, Weekes, Dana   +8 more
core   +4 more sources

Hemagglutinin sequence conservation guided stem immunogen design from influenza A H3 subtype [PDF]

, 2015
Seasonal epidemics caused by influenza A (H1 and H3 subtypes) and B viruses are a major global health threat. The traditional, trivalent influenza vaccines have limited efficacy because of rapid antigenic evolution of the circulating viruses.
Citron, Michael, Ferrara, Francesca, Flynn, Jessica A, Liang, Xiaoping, Mallajosyula, Vamsee V A, Temperton, Nigel J., Varadarajan, Raghavan   +6 more
core   +4 more sources

A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets

bioRxiv, 2022
Universal influenza vaccines have the potential to protect against continuously evolving and newly emerging influenza viruses. T cells may be an essential target of such vaccines as they can clear infected cells through recognition of conserved influenza
Koen van de Ven, J. Lanfermeijer, H. van Dijken, Hiromi Muramatsu, Caroline Vilas Boas de Melo, Stefanie Lenz, Florence Peters, Mitchell Beattie, Paulo J C Lin, J. Ferreira, J. V. D. van den Brand, D. van Baarle, N. Pardi, Jørgen de Jonge   +13 more
semanticscholar   +1 more source

The rise of companies from emerging markets in global health governance: opportunities and challenges [PDF]

, 2014
The article analyses the involvement of pharmaceutical companies from emerging markets in global health governance. It finds that they play a central role as low-cost suppliers of medicines and vaccines and, increasingly, new technologies.
ANNE ROEMER-MAHLER, Brooks, Brown, Buse, Chaudhuri, Clarke, Cooper Ramo, Drezner, Elbe, Fleury, Gold, Knight, Levy, Meyer, Petryna, Ramamurti, Roemer-Mahler, Schoofs, Wells, Whyte, Williams, Williamson, Youde, Zimmerman   +23 more
core   +1 more source

Exploring the potential public health benefits of universal influenza vaccine

Human Vaccines & Immunotherapeutics, 2019
Background: Broadly protective, long-lasting universal influenza vaccines are under development in response to low-moderate seasonal vaccine effectiveness, frequent genetic changes in circulating viruses and extended turnaround for vaccine manufacture ...
Jay V. DePasse, Mary Patricia Nowalk, Kenneth J. Smith, Jonathan M. Raviotta, Eunha Shim, Richard K. Zimmerman, Shawn T. Brown   +6 more
doaj   +1 more source

Strategy of developing nucleic acid-based universal monkeypox vaccine candidates

Frontiers in Immunology, 2022
Until May 2022, zoonotic infectious disease monkeypox (MPX) caused by the monkeypox virus (MPXV) was one of the forgotten viruses considered to be geographically limited in African countries even though few cases outside of Africa were identified ...
Dimitri Papukashvili, N. Rcheulishvili, Cong Liu, Xingyun Wang, Yunjiao He, P. Wang   +5 more
semanticscholar   +1 more source