Results 21 to 30 of about 1,366,602 (255)

Subunit Vaccine Targeting Phosphate ABC Transporter ATP-Binding Protein, PstB, Provides Cross-Protection against Streptococcus suis Serotype 2, 7, and 9 in Mice

Veterinary Sciences, 2023
Streptococcus suis is a significant pathogen in pigs and a newly emerging zoonotic agent in humans. The presence of multiple serotypes and strains with diversified sequence types in pig herds highlights the need for the identification of broadly cross ...
Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, Xiaochun Ma, Nihua Dong, Jianchao Wei, Ke Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, Zhiyong Ma, Juxiang Liu, Beibei Li   +16 more
doaj   +1 more source

The effect of respiratory viruses on immunogenicity and protection induced by a candidate universal influenza vaccine in mice.

PLoS ONE, 2019
Current approaches to influenza control rely on vaccines matched to viruses in circulation. Universal influenza vaccines would offer the advantage of providing broad protection against diverse strains of influenza virus.
Janelle Rowell, Chia-Yun Lo, Graeme E Price, Julia A Misplon, Roberta L Crim, Priyanka Jayanti, Judy Beeler, Suzanne L Epstein   +7 more
doaj   +1 more source

A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies

Vaccines, 2018
The antigenically conserved hemagglutinin stalk region is a target for universal influenza virus vaccines since antibodies against it can provide broad protection against influenza viruses of different subtypes.
Sun-Young Sunwoo, Michael Schotsaert, Igor Morozov, Anne Sally Davis, Yuhao Li, Jinhwa Lee, Chester McDowell, Philip Meade, Raffael Nachbagauer, Adolfo García-Sastre, Wenjun Ma, Florian Krammer, Juergen A. Richt   +12 more
doaj   +1 more source

Developing Universal Influenza Vaccines: Hitting the Nail, Not Just on the Head

Vaccines, 2015
Influenza viruses have a huge impact on public health. Current influenza vaccines need to be updated annually and protect poorly against antigenic drift variants or novel emerging subtypes.
Lidewij C. M. Wiersma, Guus F. Rimmelzwaan, Rory D. de Vries   +2 more
doaj   +1 more source

Chimeric Virus-like Particles Co-Displaying Hemagglutinin Stem and the C-Terminal Fragment of DnaK Confer Heterologous Influenza Protection in Mice

Viruses, 2022
Influenza virus hemagglutinin (HA) stem is currently regarded as an extremely promising immunogen for designing universal influenza vaccines. The appropriate antigen-presenting vaccine vector would be conducive to increasing the immunogenicity of the HA ...
Cui-Cui Liu, De-Jian Liu, Xin-Yu Yue, Xiu-Qin Zhong, Xuan Wu, Hai-Yan Chang, Bao-Zhong Wang, Mu-Yang Wan, Lei Deng   +8 more
doaj   +1 more source

Strengthening Vaccine Safety Systems, Research, and Regional Collaboration in Africa: A Call to Action

Vaccines
The 8th meeting of the African Advisory Committee on Vaccine Safety (AACVS), constituted in 2021, convened by the Vaccine Research and Innovation Unit within the Vaccine Preventable Diseases Program, WHO Regional Office for Africa, was held virtually ...
Beckie N. Tagbo, Chioma S. Ejekam, Winfred Oppong-Amoako, Tene Marceline Yameogo, Afework Mitiku, Dorothy O. Esangbedo, Nelisiwe Khuzwayo, Gugu Mahlangu, Samia M. Badar, Edinam A. Agbenu, Rhanda M. Adechina, Kwasi A. Nyarko   +11 more
doaj   +1 more source

PRODUCTION OF HYBRID RECOMBINANT PROTEIN Flu-Chim, CONTAINING INFLUENZA VIRUSES A AND B MAJOR EPITOPES

Инфекция и иммунитет, 2017
The influenza virus is highly contagious diseases of people, birds and mammals. Approximately 250 000– 500 000 deaths are caused by influenza epidemics worldwide yearly, and the death number may be up to millions in a possible influenza pandemic ...
I. V. Dukhovlinov, O. A. Dobrovolskaia, A. I. Orlov   +2 more
doaj   +1 more source

OVX033, a nucleocapsid-based vaccine candidate, provides broad-spectrum protection against SARS-CoV-2 variants in a hamster challenge model

Frontiers in Immunology, 2023
Spike-based COVID-19 vaccines induce potent neutralizing antibodies but their efficacy against SARS-CoV-2 variants decreases. OVX033 is a recombinant protein composed of the full-length nucleocapsid (N) protein of SARS-CoV-2 genetically fused to oligoDOM®
Charlotte Primard, Elodie Monchâtre-Leroy, Judith Del Campo, Séverine Valsesia, Elsa Nikly, Marion Chevandier, Franck Boué, Alexandre Servat, Marine Wasniewski, Evelyne Picard-Meyer, Thomas Courant, Nicolas Collin, Francisco J. Salguero, Alexandre Le Vert, Delphine Guyon-Gellin, Florence Nicolas   +15 more
doaj   +1 more source

Primary and booster immune responses to SA14-14-2 Japanese encephalitis vaccine in Korean infants

, 1999
Attenuated SA14-14-2 Japanese encephalitis (JE) vaccine has been administered safely and effectively to more than 100 million children in China since 1988 and recently, licensure of the vaccine in Korea has been sought.
박민수
core   +1 more source

Analyzing Subnational Immunization Coverage to Catch up and Reach the Unreached in Seven High-Priority Countries in the Eastern Mediterranean Region, 2019–2021

Vaccines
Yearly national immunization coverage reporting does not measure performance at the subnational level throughout the year and conceals inequalities within countries.
Kamal Fahmy, Quamrul Hasan, Md Sharifuzzaman, Yvan Hutin   +3 more
doaj   +1 more source