Results 11 to 20 of about 1,366,602 (255)

Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom [PDF]

, 2013
An analysis was undertaken to measure age-specific vaccine effectiveness (VE) of 2010/11 trivalent seasonal influenza vaccine (TIV) and monovalent 2009 pandemic influenza vaccine (PIV) administered in 2009/2010.
Ellis, J., Fleming, D.M., Pebody, R.G., Andrews, Nick, Zambon, Maria, McMenamin, J., Moore, C., Hearns, C., Carman, W., Cottrell, S., Smyth, B., Durnall, H., Watson, J.M., Robertson, Chris, Sebastian-Pillai, P., Thomas, D.R.   +15 more
core   +4 more sources

Targeting Antigens for Universal Influenza Vaccine Development

Viruses, 2021
Traditional influenza vaccines generate strain-specific antibodies which cannot provide protection against divergent influenza virus strains. Further, due to frequent antigenic shifts and drift of influenza viruses, annual reformulation and revaccination
Quyen-Thi Nguyen, Young-Ki Choi
doaj   +1 more source

Flagellin-Fused Protein Targeting M2e and HA2 Induces Innate and T-Cell Responses in Mice of Different Genetic Lines

Vaccines, 2022
Efficient control of influenza A infection can potentially be achieved through the development of broad-spectrum vaccines. Recombinant proteins incorporating conserved influenza A virus peptides are one of the platforms for the development of cross ...
Liudmila A. Stepanova, Marina A. Shuklina, Kirill A. Vasiliev, Anna A. Kovaleva, Inna G. Vidyaeva, Yana A. Zabrodskaya, Alexandr V. Korotkov, Liudmila M. Tsybalova   +7 more
doaj   +1 more source

Will the public take a universal influenza vaccine?: the need for social and behavioral science research

Human Vaccines & Immunotherapeutics, 2020
Every influenza season, uptake of the flu vaccine falls short of the Healthy People 2020 goal of at least 70% of adults being vaccinated. Mixed methods research finds multiple factors associated with this phenomenon including misconceptions about the ...
Sandra Crouse Quinn, Amelia Jamison
doaj   +1 more source

Expression of Influenza M2e-NP Recombinant Fusion Protein in Escherichia coli BL21 (DE3) and Its Binding to Antibodies

Vaccines, 2022
The current influenza vaccines only confer protection against the circulating influenza subtypes, therefore universal vaccines are needed to prevent upcoming influenza outbreaks caused by emerging influenza subtypes. The extracellular domain of influenza
Mei Peng Tan, Noorjahan Banu Mohamed Alitheen, Wen Siang Tan, Wei Boon Yap   +3 more
doaj   +1 more source

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래
core   +1 more source

Universal Vaccine Development Against COVID-19 and Influenza [PDF]

E3S Web of Conferences
Universal vaccines appeared as a favorable solution for the rapid mutation of viruses that cause pandemics. Sufficient immune protection, safe and efficient production methods, and low-cost funding are ideal properties for universal vaccines.
Suo Zhaotaize
doaj   +1 more source

Effectiveness and safety of injectable human papilloma virus vaccine administered as eyedrops

, 2023
Mucosal vaccines have the advantages of ease of administration and the induction of strong mucosal immunity and a systemic immune response. Recently, the eye mucosa has been shown to be an effective and safe alternative vaccination route against ...
윤상철, 서경률, 이지혜
core   +1 more source

Design, evaluation, and immune simulation of potentially universal multi-epitope mpox vaccine candidate: focus on DNA vaccine

Frontiers in Microbiology, 2023
Monkeypox (mpox) is a zoonotic infectious disease caused by the mpox virus. Mpox symptoms are similar to smallpox with less severity and lower mortality.
Nino Rcheulishvili, Jiawei Mao, Dimitri Papukashvili, Shunping Feng, Cong Liu, Xingyun Wang, Yunjiao He, Peng George Wang   +7 more
doaj   +1 more source

Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis

, 2020
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones ...
권기웅, 신성재
core   +1 more source