Results 61 to 70 of about 524,435 (262)

Making Students Aware of the Universal Human Values

open access: yesACROSS, 2021
This increases the importance of higher education as a factor of socialization of students, as well as the role of the university educational process in the personal and professional development and especially that of the future teacher of the younger ...
Nadiia KICHUK, Antonina KICHUK
doaj  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

CIVILIZATION AND UNIVERSAL VALUES

open access: yesInternational Journal of Innovative Technologies in Social Science
Morality is no longer a single, unified concept. Instead, it has evolved into a diverse set of ethics that are influenced by various cognitive domains. These dimensions collectively aim to establish a universal moral framework in contemporary civilization.
Dekkar Mohammed Amine   +1 more
openaire   +2 more sources

Universal Banking: A Shareholder Value Perspective [PDF]

open access: yesSSRN Electronic Journal, 1996
In their historical development, organizational structure, and strategic direction, universal banks constitute multi-product firms within the financial services sector. Certainly within their home environments, universal banks effectively target most or all client-segments, and make an effort to provide each with a full range of the appropriate ...
openaire   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

From Values to Religion

open access: yesRIMCIS, 2012
Each individual is guided by values that determine his behaviour. A recurrent distinction concerns the difference between applied values and final values, therefore between values concerning individual practices and values which represent real goals to ...
Roberto Cipriani
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Analysis of the content of process-oriented culture in modern organisations

open access: yesВестник университета
This article is devoted to the study of the content of process-oriented organizational culture. The main questions in it are whether there is a composition of universal values defined by the methodology of business process management and whether the ...
D. V. Bashmakov
doaj   +1 more source

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