Results 71 to 80 of about 1,105,380 (358)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Znaczenie średniowiecznej filozofii w rozwoju nauk
Studia Koszalińsko-Kołobrzeskie, 2016 One of the major mistakes in assessing the significance of medieval philosophy for the development of science is omitting all the historical context in which philosophy and sciences evolved.
Edward Sienkiewicz
doaj +1 more source
Universality class in conformal inflation [PDF]
, 2013 We develop a new class of chaotic inflation models with spontaneously broken conformal invariance. Observational consequences of a broad class of such models are stable with respect to strong deformations of the scalar potential.
R. Kallosh, Andrei Linde
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Universality versus variation in the conceptualization of anger: A question of methodology
Russian Journal of LinguisticsCognitive linguistic investigations into the metaphorical conceptualization of anger suggest that languages are remarkably similar on a schematic level, with intensity and control as two, possibly universal dimensions underlying the metaphorical ...
Zoltán Kövecses +3 more
doaj +1 more source
Primordial gravitational waves for universality classes of pseudoscalar inflation [PDF]
, 2016 Current bounds from the polarization of the CMB predict the scale-invariant gravitational wave (GW) background of inflation to be out of reach for upcoming GW interferometers. This prospect dramatically changes if the inflaton is a pseudoscalar, in which
V. Domcke, M. Pieroni, P. Bin'etruy
semanticscholar +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Media Culture and Society, 2017 This contribution compares personalisation strategies of public service media (PSM) and how these are reconciled with PSM’s core values, especially universality.
H. Van den Bulck, Hallvard Moe
semanticscholar +1 more source
Lepton universality violation with lepton flavor conservation in B-meson decays [PDF]
, 2015 A bstractAnomalies in semileptonic B-meson decays present interesting patterns that might be revealing the shape of the new physics to come. Under the assumption that neutrino and charged lepton mass terms are the only sources of flavor violation and ...
R. Alonso, B. Grinstein, J. Camalich
semanticscholar +1 more source