Results 41 to 50 of about 108,259 (287)

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Magic of Words: Lexemes with Semantics ‘Spell’ and ‘to Spell’ in Vepsian (Etymological-Semantic and Linguo-Geographical Aspects)

Научный диалог, 2022
A comparative analysis of the Veps language lexemes with the semantics ‘spell’ (puheg, puitoomine), as well as verbs with the meaning ‘to spell; pronounce incantations.
O. Yu. Zhukova, N. G. Zaitseva
doaj   +1 more source

A formal theory of conceptual modeling universals [PDF]

, 2004
Conceptual Modeling is a discipline of great relevance to several areas in Computer Science. In a series of papers [1,2,3] we have been using the General Ontological Language (GOL) and its underlying upper level ontology, proposed in [4,5], to evaluate ...
Guizzardi, Giancarlo, Sinderen, Marten van, Wagner, Gerd   +2 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The idea of being is not uniquely innate

Principia: An International Journal of Epistemology, 2016
According to the Italian philosopher Antonio Rosmini (1797-1855), being is an  innate idea that is requisite for contemplating anything. He emphatically claims that it is the one and only innate idea.
Inge-Bert Täljedal
doaj   +1 more source

Language universals and interlinguistic variation [PDF]

, 1975
Actually, the title should include intralinguistic variation along with the interlinguistic one. For variation within one and the same language is the thing which directly presents itself to the observation while it still remains to be demonstrated that ...
Seiler, Hansjakob
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Logic in the tradition of Prabhacandra [PDF]

, 2014
The characterization of truth-preserving arguments is a core issue in India and received the detailed attention of philosophers. This chapter presents Prabhācandra’s theory of inference from the eleventh century, stressing its uniqueness and detailed ...
Gorisse, Marie-Hélène
core   +2 more sources

UNIVERSITY of Universities

, 2022
La red “UNIVERSITY of Universities” no cesa de amoldarse a los continuos cambios de las circunstancias docentes, económicas, de conflictos internacionales y por supuesto de pandemia. Lo importante es entender cada restricción como una oportunidad de proyecto.
Sánchez Merina, Francisco Javier, Alvado Bañón, Joaquín, Nobile, Maria Luna, Devereux, Mike, Menikou, Markella   +4 more
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source