Results 61 to 70 of about 108,259 (287)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

The Universals of Human Nature: A Method of Their Detection through Scientific Evidence and Literary Fiction

open access: yesProfil
With the arrival of biological evolutionism and behaviourism, the concept of human nature has become very unstable. The proposed method for detecting the features of human nature based on discomfort allows us to reconsider human nature and regard the ...
Tomáš Károly
doaj   +1 more source

THE REFLECTION ON THE CONCEPT OF UNIVERSALS AND ITS SOCIAL-HISTORICAL VERIFICATION

open access: yesCхід, 2021
In this article, the author reviews the concept of singular and general. The analysis focus on the problem of universals during social-historical transformation.
IHOR PASKO
doaj   +1 more source

The Unity of a Tractarian Fact [PDF]

open access: yes, 2007
It is not immediately clear from Wittgenstein’s Tractatus how to connect his idea there of an object with the logical ontologies of Frege and Russell. Toward clarification on this matter, this paper compares Russell’s and Wittgenstein’s versions of the ...
Johnston, Colin
core   +1 more source

Universal Peptidomimetics [PDF]

open access: yesJournal of the American Chemical Society, 2010
This paper concerns peptidomimetic scaffolds that can present side chains in conformations resembling those of amino acids in secondary structures without incurring excessive entropic or enthalpic penalties. Compounds of this type are referred to here as minimalist mimics.
Eunhwa, Ko   +5 more
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A Modest Proposal for Resolving the Apparently Never-Ending Evolution Debate: Reconsidering the Question

open access: yesStudia Gilsoniana, 2019
The author makes an attempt to show why (1) Darwin’s teaching in The Origin of Species by Means of Natural Selection and The Descent of Man and Selection in Relation to Sex cannot be “scientific” in a modern, classical, or any, sense and that ...
Peter A. Redpath
doaj   +1 more source

Sebastian Izquierdo on Universals [PDF]

open access: yes, 2017
The paper deals with the theory of universals of Sebastian Izquierdo, a Spanish Jesuit author working in Rome, as he formulated and defended it in Disputation 17 of his major philosophical work The Lighthouse of Sciences, published in Lyon in 1659 ...
Novotný, Daniel D.
core  

Anatomical information science [PDF]

open access: yes, 2005
The Foundational Model of Anatomy (FMA) is a map of the human body. Like maps of other sorts – including the map-like representations we find in familiar anatomical atlases – it is a representation of a certain portion of spatial reality as it exists at ...
Kumar, Anand   +4 more
core   +2 more sources

Home - About - Disclaimer - Privacy