Results 81 to 90 of about 108,259 (287)

Basic Verbs of Possession

open access: yesCogniTextes, 2010
Verbs of possession such as HAVE and GIVE have been extensively studied both typologically and from a cognitive linguistic perspective. The present study presents an analysis of possession verbs as a semantic field with a focus on the most basic verbs ...
Åke Viberg
doaj   +1 more source

On the Genealogy of Universals: The Metaphysical Origins of Analytic Philosophy [PDF]

open access: yes, 2018
The concepts of particular and universal have grown so familiar that their significance has become difficult to discern, like coins that have been passed back and forth too many times, worn smooth so their values can no longer be read.
MacBride, Fraser
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Instantiation in Trope Theory [PDF]

open access: yes, 2018
The concept of instantiation is realized differently across a variety of metaphysical theories. A certain realization of the concept in a given theory depends on what roles are specified and associated with the concept and its corresponding term as well ...
Fisher, A. R. J.
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

A comparative syntax of internally-headed relative clauses in Gur

open access: yesGlossa, 2017
Gur (or Mabia) languages which are spoken in West Africa have so-called internally-headed relative clauses (IHRCs), but they have not received serious attention in syntactic and typological research on IHRCs.
Adams Bodomo   +5 more
doaj   +2 more sources

New desiderata for biomedical terminologies [PDF]

open access: yes, 2008
It is only by fixing on agreed meanings of terms in biomedical terminologies that we will be in a position to achieve that accumulation and integration of knowledge that is indispensable to progress at the frontiers of biomedicine.
Smith, Barry
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Does Ockham’s razor matter to the problem of universals?

open access: yesGriot
This paper investigates how Ockham’s Razor can be applied to compare and evaluate solutions to the Problem of Universals. Initially, I discuss three formulations of this principle.
Valdetonio Pereira de Alencar
doaj   +1 more source

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