Results 81 to 90 of about 653,375 (291)

College and University Library Statistics

open access: yesCollege & Research Libraries, 1947
published or submitted for publication ; Made available in DSpace on 2013-01-10T22:25:24Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) crl_08_03_part_1_259_opt.pdf: 3235472 bytes, checksum: 34ba8f879b9bd7770292c9d537d7db47 (MD5) Previous issue date: 1947 ...
openaire   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

2008 Index of Higher Education Fundraising Performance: Summary of Annual Fund Key Performance Indicators [PDF]

open access: yes, 2009
Analyses are based on fiscal year 2008 donor transactions from 33 public and 32 private universities and ...

core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Pollen and Floral Organ Morphology of 18 Oil-Tea Genotypes and Its Systematic Significance

open access: yesHorticulturae
Oil-tea belongs to the Camellia genus, an important oil crop in China. However, oil-tea is taxonomically challenging due to its morphological variation, polyploidy, and interspecific hybridization.
Qian Yin   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Scientific Methods and Sacred Matters: On Methodological Naturalism, Divine Agency, and Christians in Science

open access: yesZygon
This article critically analyzes the debate surrounding methodological naturalism (MN) within the context of scientific inquiry, focusing on the arguments put forth by Andrew Torrance on the one hand and John Perry and Sarah Lane Ritchie on the other. It
Mitchell Mallary
doaj   +2 more sources

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