Results 91 to 100 of about 78,497,869 (306)

Perfil clínico-epidemiológico de pacientes com doença de Chagas no Hospital Universitário de Maringá, Paraná, Brasil

Cadernos de Saúde Pública
Este trabalho descreveu o perfil clínico-epidemiológico de pacientes com doença de Chagas atendidos no ambulatório e na internação do Hospital Universitário de Maringá (HUM), Paraná, Brasil, entre maio de 1998 a maio de 2003.
Carlos Eduardo Bozelli, Silvana Marques de Araújo, Ana Lúcia Falavigna Guilherme, Mônica Lúcia Gomes   +3 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

University Hospitals Staff Conference, October 2, 1930

, 1930
University of Minnesota. University of Minnesota Hospitals. (1930). University Hospitals Staff Conference, October 2, 1930.
University of Minnesota. University of Minnesota Hospitals
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

University Hospitals Annual Report, 1955-1956

, 1956
University of Minnesota. University Hospitals and Clinics. (1956). University Hospitals Annual Report, 1955-1956.
University of Minnesota. University Hospitals and Clinics
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Comparison of Physical Space of Pediatric Wards in Isfahan Hospitals with Standards

مدیریت اطلاعات سلامت, 2008
Introduction: Pediatric wards are places for care of children with physical and psychological problems. These places should be designed to reduce anxiety and Cather for children’s emotional and physical needs.
Mahmood Keyvanara, Leila Roholamin
doaj  

Perioperative practice variations between university and private hospitals in total knee arthroplasty: a retrospective comparative study

Acta Orthopaedica et Traumatologica Turcica
Objective: Differences in healthcare delivery between university and private hospitals may influence perioperative management practices in orthopedic surgery. However, objective data comparing these settings in Türkiye remain limited.
Murat Köken, Danyal Gümüş, Burak Akan   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

University Hospitals Annual Report, 1954-1955

, 1955
University of Minnesota. University Hospitals and Clinics. (1955). University Hospitals Annual Report, 1954-1955.
University of Minnesota. University Hospitals and Clinics
core