Results 111 to 120 of about 78,497,869 (306)

Non-specialized inpatient care provided by university hospitals in Japan

Risk Management and Healthcare Policy, 2008
Shin-ichi ToyabeCrisis Management Office, Niigata University Hospital, Niigata City, JapanAbstract: In Japan, all citizens are covered by the national insurance system in which universal free access to healthcare services is promised to everybody.
Shin-ichi Toyabe
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

University Hospitals General Staff Meeting, April 7, 1932

, 1932
University of Minnesota. University of Minnesota Hospitals. (1932). University Hospitals General Staff Meeting, April 7, 1932.
University of Minnesota. University of Minnesota Hospitals
core  

Potential drug-drug interactions in a Brazilian teaching hospital: age-related differences?

Revista de Ciências Farmacêuticas Básica e Aplicada, 2015
This study proposes to measure frequency and to characterize the profile of potential drug interactions (pDDI) in a general medicine ward of a teaching hospital.
Daniela Oliveira de Melo, Eliane Ribeiro, Sílvia Storpirtis   +2 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

University Hospitals Staff Meeting Bulletin, April 12, 1934

, 1934
University of Minnesota. University of Minnesota Hospitals. (1934). University Hospitals Staff Meeting Bulletin, April 12, 1934.
University of Minnesota. University of Minnesota Hospitals
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

University Hospitals General Staff Meeting, December 3, 1931

, 1931
University of Minnesota. University of Minnesota Hospitals. (1931). University Hospitals General Staff Meeting, December 3, 1931.
University of Minnesota. University of Minnesota Hospitals
core  

Environmental disclosure of healthcare waste in public university hospitals in Brazil: diagnosis and proposal of a disclosure model aimed at transparency and sustainability

Revista Ambiente Contábil
Purpose: Propose an environmental disclosure model for healthcare waste aimed at public university hospitals in Brazil. Methodology: The research, of a descriptive nature, employed content analysis of reports published by university hospitals and ...
Fabrícia Silva da Rosa, Juliana dos Anjos   +1 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source